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Literature summary extracted from

  • Kelleher, D.J.; Gilmore, R.
    DAD1, the defender against apoptotic cell death, is a subunit of the mammalian oligosaccharyltransferase (1997), Proc. Natl. Acad. Sci. USA, 94, 4994-4999.
    View publication on PubMedView publication on EuropePMC

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.4.99.18 microsome rough Canis lupus familiaris
-
-
2.4.99.18 rough endoplasmic reticulum
-
 Canis lupus familiaris 5791
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.4.99.18 lipid-linked oligosaccharide + unfolded nascent polypeptide chain Canis lupus familiaris the DAD1 subunit is a defender against apoptotic cell death ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.4.99.18 Canis lupus familiaris
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.4.99.18 pancreas
-
 Canis lupus familiaris
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.4.99.18 dolichyl diphosphooligosaccharide + protein L-asparagine
-
 Canis lupus familiaris dolichyl diphosphate + glycoprotein with the oligosaccharide chain attached by N-glycosyl-linkage to protein L-asparagine
-
 ?
2.4.99.18 lipid-linked oligosaccharide + unfolded nascent polypeptide chain the DAD1 subunit is a defender against apoptotic cell death Canis lupus familiaris ?
-
 ?

Subunits

EC Number Subunits Comment Organism
2.4.99.18 More the 12500 Da DAD1 protein is a tightly associated subunit of the OST both in intact membrane and in purified enzyme Canis lupus familiaris