EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
2.3.3.10 | 5,5'-dithiobis(2-nitrobenzoate) | Ellman's reagent | Gallus gallus | |
2.3.3.10 | 5,5'-dithiobis(2-nitrobenzoate) | - |
Saccharomyces cerevisiae | |
2.3.3.10 | acetoacetyl-CoA | - |
Gallus gallus | |
2.3.3.10 | acetoacetyl-CoA | - |
Saccharomyces cerevisiae | |
2.3.3.10 | p-chloromercuribenzoate | - |
Gallus gallus | |
2.3.3.10 | p-chloromercuribenzoate | - |
Saccharomyces cerevisiae |
EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
2.3.3.10 | 0.3 | - |
acetyl-CoA | 0.1 mM acetoacetyl-CoA | Gallus gallus |
EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|---|
2.3.3.10 | cytoplasm | - |
Gallus gallus | 5737 | - |
2.3.3.10 | cytoplasm | - |
Saccharomyces cerevisiae | 5737 | - |
2.3.3.10 | cytosol | - |
Gallus gallus | 5829 | - |
2.3.3.10 | cytosol | - |
Saccharomyces cerevisiae | 5829 | - |
2.3.3.10 | mitochondrion | - |
Gallus gallus | 5739 | - |
EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|---|
2.3.3.10 | 55000 | - |
2 * 55000, synthase II, SDS-PAGE | Gallus gallus |
2.3.3.10 | 100000 | - |
cytosolic enzyme, sedimentation equilibrium | Gallus gallus |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.3.3.10 | acetyl-CoA + acetoacetyl-CoA + H2O | Saccharomyces cerevisiae | - |
(S)-3-hydroxy-3-methylglutaryl-CoA + CoA | - |
ir | |
2.3.3.10 | acetyl-CoA + acetoacetyl-CoA + H2O | Gallus gallus | cytosolic synthase catalyzes the second step of cholesterogenesis from acetyl-CoA | (S)-3-hydroxy-3-methylglutaryl-CoA + CoA | - |
ir | |
2.3.3.10 | acetyl-CoA + acetoacetyl-CoA + H2O | Gallus gallus | mitochondrial enzyme of liver functions in ketogenesis, its cytoplasmic counterpart participates in cholesterogenesis | (S)-3-hydroxy-3-methylglutaryl-CoA + CoA | - |
ir |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.3.3.10 | Gallus gallus | - |
chicken | - |
2.3.3.10 | Saccharomyces cerevisiae | - |
- |
- |
EC Number | Purification (Comment) | Organism |
---|---|---|
2.3.3.10 | cytosolic synthase | Gallus gallus |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
2.3.3.10 | liver | - |
Gallus gallus | - |
EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|---|
2.3.3.10 | 0.3 | - |
- |
Gallus gallus |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.3.3.10 | acetyl-CoA + 3'-dephospho-CoA + H2O | - |
Gallus gallus | acetyldephospho-CoA + CoA | - |
? | |
2.3.3.10 | acetyl-CoA + acetoacetyl-CoA + H2O | - |
Gallus gallus | (S)-3-hydroxy-3-methylglutaryl-CoA + CoA | - |
ir | |
2.3.3.10 | acetyl-CoA + acetoacetyl-CoA + H2O | - |
Saccharomyces cerevisiae | (S)-3-hydroxy-3-methylglutaryl-CoA + CoA | - |
ir | |
2.3.3.10 | acetyl-CoA + acetoacetyl-CoA + H2O | cytosolic synthase catalyzes the second step of cholesterogenesis from acetyl-CoA | Gallus gallus | (S)-3-hydroxy-3-methylglutaryl-CoA + CoA | - |
ir | |
2.3.3.10 | acetyl-CoA + acetoacetyl-CoA + H2O | mitochondrial enzyme of liver functions in ketogenesis, its cytoplasmic counterpart participates in cholesterogenesis | Gallus gallus | (S)-3-hydroxy-3-methylglutaryl-CoA + CoA | - |
ir |
EC Number | Subunits | Comment | Organism |
---|---|---|---|
2.3.3.10 | dimer | 2 * 55000, synthase II, SDS-PAGE | Gallus gallus |
EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|---|
2.3.3.10 | 9.4 | - |
- |
Gallus gallus |
EC Number | pH Minimum | pH Maximum | Comment | Organism |
---|---|---|---|---|
2.3.3.10 | 8 | 9.6 | - |
Gallus gallus |