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Literature summary extracted from

  • Lichti, U.; Ben, T.; Yuspan, S.H.
    Retinoic acid-induced transglutaminase in mouse epidermal cells is distinct from epidermal transglutaminase (1985), J. Biol. Chem., 260, 1422-1426.
    View publication on PubMed

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.3.2.13 0.051
-
 putrescine retinoic-acid-induced enzyme Mus musculus
2.3.2.13 0.065
-
 putrescine retinoic acid induced transglutaminase Mus musculus
2.3.2.13 0.098 0.106 putrescine enzyme induced by 12-O-tetradecanoylphorbol-13-acetate or Ca2+ Mus musculus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.3.2.13 soluble retinoic acid induced enzyme Mus musculus
-
-

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
2.3.2.13 Ca2+ requirement Mus musculus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.3.2.13 protein-bound gamma-glutamine + alkylamine Mus musculus epidermal enzyme involved in formation of cornified envelope protein N5-alkylglutamine + NH3
-
 ?
2.3.2.13 protein-bound gamma-glutamine + alkylamine Mus musculus BALB/c epidermal enzyme involved in formation of cornified envelope protein N5-alkylglutamine + NH3
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.3.2.13 Mus musculus
-
 BALB/c strain
-
2.3.2.13 Mus musculus BALB/c
-
 BALB/c strain
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.3.2.13 epidermal cell primary and MCA3A1-cell line, retinoic acid induced enzyme differs from normal epidermal enzyme Mus musculus
-
2.3.2.13 epidermis subcellular distribution Mus musculus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.2.13 protein-bound gamma-glutamine + alkylamine epidermal enzyme involved in formation of cornified envelope Mus musculus protein N5-alkylglutamine + NH3
-
 ?
2.3.2.13 protein-bound gamma-glutamine + alkylamine epidermal enzyme involved in formation of cornified envelope Mus musculus BALB/c protein N5-alkylglutamine + NH3
-
 ?
2.3.2.13 putrescine + casein
-
 Mus musculus ?
-
 ?
2.3.2.13 putrescine + casein
-
 Mus musculus BALB/c ?
-
 ?

Temperature Stability [°C]

EC Number Temperature Stability Minimum [°C] Temperature Stability Maximum [°C] Comment Organism
2.3.2.13 25
-
 at least 30 min stable, pH 9.0, retinoic acid induced enzyme Mus musculus
2.3.2.13 37
-
 retinoic acid induced transgutaminase, loss of approx. 75% activity after 10 min at pH 9, epidermal transglutaminase, 25% loss of activity after 20 min, pH 9.0 Mus musculus

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.3.2.13 9.5
-
-
 Mus musculus

pH Stability

EC Number pH Stability pH Stability Maximum Comment Organism
2.3.2.13 9
-
 thermolabile: t1/2: 3-4 min, 37°C, retinoic acid induced enzyme, 20% loss of activity within 20 min, epidermal enzyme Mus musculus