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Literature summary extracted from

  • Korner, G.; Schneider, D.E.; Purdon, M.A.; Bjornsson, T.D.
    Bovine aortic endothelial cell transglutaminase. Enzyme characterization and regulation of activity (1989), Biochem. J., 262, 633-641.
    View publication on PubMedView publication on EuropePMC

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.3.2.13 Dansylcadaverine 0.0019 mM, 50% inhibition Bos taurus
2.3.2.13 Dansylcadaverine 0.0019 mM, 50% inhibition Rattus norvegicus
2.3.2.13 methylamine 1.8 mM, 50% inhibition Bos taurus
2.3.2.13 methylamine 1.8 mM, 50% inhibition Rattus norvegicus
2.3.2.13 additional information not inhibited by mono- and dimethylated dansylcadaverine Bos taurus
2.3.2.13 additional information not inhibited by mono- and dimethylated dansylcadaverine Rattus norvegicus
2.3.2.13 spermine 0.17 mM, 50% inhibition Bos taurus
2.3.2.13 spermine 0.17 mM, 50% inhibition Rattus norvegicus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.3.2.13 0.203
-
 putrescine tissue transglutaminase from endothelial cells Bos taurus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.3.2.13 soluble
-
 Rattus norvegicus
-
-
2.3.2.13 soluble depending on state of cell-proliferation, intracellular distribution Bos taurus
-
-

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
2.3.2.13 Ca2+ requirement Rattus norvegicus
2.3.2.13 Ca2+ requirement Bos taurus
2.3.2.13 Ca2+ no activity below 1.25 mM, maximal activity at 2.5 mM and above, half-maximal activity at approx. 1.5 mM Bos taurus

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.3.2.13 80000
-
 liver transglutaminase, gel filtration Rattus norvegicus
2.3.2.13 88000
-
 tissue transglutaminase, gel filtration Bos taurus

Organism

EC Number Organism UniProt Comment Textmining
2.3.2.13 Bos taurus
-
 higher activity in 100% confluent endothelial cells than in 50% confluent cells
-
2.3.2.13 Rattus norvegicus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.3.2.13 partial Bos taurus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.3.2.13 endothelium aortic cell suspension culture Bos taurus
-
2.3.2.13 liver
-
 Rattus norvegicus
-
2.3.2.13 liver
-
 Bos taurus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.2.13 putrescine + N,N'-dimethylcasein
-
 Rattus norvegicus ?
-
 ?
2.3.2.13 putrescine + N,N'-dimethylcasein
-
 Bos taurus ?
-
 ?

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
2.3.2.13 37
-
 assay at Rattus norvegicus
2.3.2.13 37
-
 assay at Bos taurus