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Literature summary extracted from

  • Martin, C.R.
    Structure, function, and regulation of the chalcone synthase (1993), Int. Rev. Cytol., 147, 233-284.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.3.1.74 apigenin
-
 Secale cereale
2.3.1.74 CoA 50% inhibition at 0.01 mM Petroselinum crispum
2.3.1.74 CoA
-
 Secale cereale
2.3.1.74 Kievitone
-
 Phaseolus vulgaris
2.3.1.74 luteolin
-
 Secale cereale
2.3.1.74 naringenin 50% inhibition at 0.01 mM Petroselinum crispum
2.3.1.74 naringenin
-
 Phaseolus vulgaris
2.3.1.74 naringenin 0.1 mM Secale cereale
2.3.1.74 naringenin chalcone
-
 Daucus carota
2.3.1.74 naringenin chalcone 0.1 mM Secale cereale

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.74 Daucus carota
-
-
-
2.3.1.74 Petroselinum crispum
-
-
-
2.3.1.74 Phaseolus vulgaris
-
-
-
2.3.1.74 Pinus sylvestris
-
 Scots pine
-
2.3.1.74 Secale cereale
-
-
-
2.3.1.74 Silene sp.
-
-
-
2.3.1.74 Sinapis alba
-
 white mustard
-
2.3.1.74 Verbena sp.
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.1.74 caffeoyl-CoA + 3 malonyl-CoA
-
 Daucus carota eriodictyol + 4 CoA + 3 CO2
-
 ?
2.3.1.74 caffeoyl-CoA + 3 malonyl-CoA
-
 Secale cereale eriodictyol + 4 CoA + 3 CO2
-
 ?
2.3.1.74 caffeoyl-CoA + 3 malonyl-CoA
-
 Silene sp. eriodictyol + 4 CoA + 3 CO2
-
 ?
2.3.1.74 caffeoyl-CoA + 3 malonyl-CoA less efficient than 4-coumaroyl-CoA Verbena sp. eriodictyol + 4 CoA + 3 CO2
-
 ?
2.3.1.74 cinnamoyl-CoA + malonyl-CoA
-
 Sinapis alba 5,7-dihydroxyflavanone + CoA + CO2
-
 ?
2.3.1.74 cinnamoyl-CoA + malonyl-CoA
-
 Pinus sylvestris 5,7-dihydroxyflavanone + CoA + CO2 i.e. pinocembrin ?
2.3.1.74 malonyl-CoA + 4-coumaroyl-CoA
-
 Phaseolus vulgaris naringenin chalcone + CoA + CO2
-
 ?
2.3.1.74 malonyl-CoA + 4-coumaroyl-CoA
-
 Petroselinum crispum naringenin chalcone + CoA + CO2
-
 ?
2.3.1.74 malonyl-CoA + 4-coumaroyl-CoA
-
 Daucus carota naringenin chalcone + CoA + CO2
-
 ?
2.3.1.74 malonyl-CoA + 4-coumaroyl-CoA
-
 Secale cereale naringenin chalcone + CoA + CO2
-
 ?
2.3.1.74 malonyl-CoA + 4-coumaroyl-CoA
-
 Silene sp. naringenin chalcone + CoA + CO2
-
 ?
2.3.1.74 malonyl-CoA + 4-coumaroyl-CoA
-
 Verbena sp. naringenin chalcone + CoA + CO2
-
 ?