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Literature summary extracted from

  • Schuz, R.; Heller, W.; Hahlbrock, K.
    Substrate specificity of chalcone synthase from Petroselinum hortense. Formation of phloroglucinol derivatives from aliphatic substrates (1983), J. Biol. Chem., 258, 6730-6734.
    View publication on PubMed

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.3.1.74 0.0007
-
 hexanoyl-CoA
-
 Petroselinum crispum
2.3.1.74 0.0022
-
 4-coumaroyl-CoA
-
 Petroselinum crispum

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.3.1.74 4-coumaroyl-CoA + 3 malonyl-CoA Petroselinum crispum
-
 naringenin chalcone + 4 CoA + 3 CO2
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.74 Petroselinum crispum
-
 parsley
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.3.1.74 cell suspension culture
-
 Petroselinum crispum
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.1.74 2 malonyl-CoA + acetyl-CoA poor substrate Petroselinum crispum 4-hydroxy-6-methyl-2-pyrone + 3 CoA + 2 CO2 i.e. triacetic acid lactone ?
2.3.1.74 4-coumaroyl-CoA + 3 malonyl-CoA
-
 Petroselinum crispum naringenin chalcone + 4 CoA + 3 CO2
-
 ?
2.3.1.74 malonyl CoA + 4-coumaroyl-CoA + NADH
-
 Petroselinum crispum 6'-deoxychalcone + CoA + CO2 + NAD+
-
 ?
2.3.1.74 malonyl-CoA + benzoyl-CoA poor substrate at pH 8, most efficient substrate at pH 6.5 Petroselinum crispum phlorobenzophenone + CO2 + CoA
-
 ?
2.3.1.74 malonyl-CoA + butyryl-CoA
-
 Petroselinum crispum phlorobutyrophenone + CO2 + CoA
-
 ?
2.3.1.74 malonyl-CoA + hexanoyl-CoA
-
 Petroselinum crispum phlorocaprophenone + CO2 + CoA
-
 ?
2.3.1.74 malonyl-CoA + octanoyl-CoA poor substrate Petroselinum crispum 1-(2,4,6-trihydroxyphenyl)-octan-1-one + CoA + CO2
-
 ?