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Literature summary extracted from

  • Whitehead, I.M.; Dixon, R.A.
    Chalcone synthase from cell suspension cultures of phaseolus vulgaris L. (1983), Biochim. Biophys. Acta, 747, 298-303.
No PubMed abstract available

Activating Compound

EC Number Activating Compound Comment Organism Structure
2.3.1.74 2-mercaptoethanol 2fold increase at 20 mM Phaseolus vulgaris
2.3.1.74 dithiothreitol 4fold increase at 20 mM Phaseolus vulgaris

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.3.1.74 2'-hydroxygenistein
-
 Phaseolus vulgaris
2.3.1.74 cerulenin
-
 Phaseolus vulgaris
2.3.1.74 Dalbergioidin
-
 Phaseolus vulgaris
2.3.1.74 isoliquiritigenin
-
 Phaseolus vulgaris
2.3.1.74 Kievitone 50% inhibition at 0.001 mM Phaseolus vulgaris
2.3.1.74 naringenin
-
 Phaseolus vulgaris

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.3.1.74 0.0023
-
 4-coumaroyl-CoA
-
 Phaseolus vulgaris
2.3.1.74 0.0214
-
 malonyl-CoA
-
 Phaseolus vulgaris

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.3.1.74 77000
-
 gel filtration Phaseolus vulgaris

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.74 Phaseolus vulgaris
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.3.1.74 31fold Phaseolus vulgaris

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.3.1.74 cell suspension culture
-
 Phaseolus vulgaris
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
2.3.1.74 0.00176
-
-
 Phaseolus vulgaris

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.1.74 malonyl-CoA + 4-coumaroyl-CoA
-
 Phaseolus vulgaris naringenin chalcone + CoA + CO2
-
 ?

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
2.3.1.74 40
-
-
 Phaseolus vulgaris

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.3.1.74 8
-
-
 Phaseolus vulgaris

Ki Value [mM]

EC Number Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
2.3.1.74 0.0207
-
 Kievitone
-
 Phaseolus vulgaris