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Literature summary extracted from

  • Kelley, M.; Vessey, D.A.
    Characterization of the acyl-CoA:amino acid N-acyltransferases from primate liver mitochondria (1994), J. Biochem. Toxicol., 9, 153-158.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.3.1.192 KCl 80 mM KC1, ca. 30% inhibition, inhibition is seen at all concentrations of glutamine up to 150 mM Homo sapiens
2.3.1.192 additional information human enzyme is insensitive to salts Homo sapiens

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.3.1.192 120
-
 L-glutamine pH 8.0, 30°C Homo sapiens

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.3.1.71 mitochondrion
-
 Homo sapiens 5739
-
2.3.1.192 mitochondrion
-
 Homo sapiens 5739
-

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.3.1.71 30500
-
 gel filtration Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.71 Homo sapiens
-
-
-
2.3.1.192 Homo sapiens
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.3.1.71 partial Homo sapiens
2.3.1.192 partial Homo sapiens

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.3.1.71 liver
-
 Homo sapiens
-
2.3.1.192 liver
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.1.71 benzoyl-CoA + glycine
-
 Homo sapiens CoA + N-benzoylglycine
-
 ?
2.3.1.71 heptanoyl-CoA + glycine 9.5% of the activity with benzoyl-CoA Homo sapiens CoA + N-heptanoylglycine
-
 ?
2.3.1.71 indoleacetyl-CoA + glycine
-
 Homo sapiens CoA + N-indoleacetylglycine
-
 ?
2.3.1.71 isovaleryl-CoA + glycine 9.1% of the activity with benzoyl-CoA Homo sapiens CoA + N-isovalerylglycine
-
 ?
2.3.1.71 n-butyryl-CoA + glycine 28% of the activity with benzoyl-CoA Homo sapiens CoA + N-butyrylglycine
-
 ?
2.3.1.71 salicyl-CoA + glycine 22% of the activity with benzoyl-CoA Homo sapiens CoA + salicyluric acid
-
 ?
2.3.1.192 1-naphtylacetyl-CoA + L-glutamine 3-5% of the rate with phenacetyl-CoA Homo sapiens ? + CoA
-
 ?
2.3.1.192 indoleacetyl-CoA + L-glutamine 3-5% of the rate with phenacetyl-CoA Homo sapiens ? + CoA
-
 ?
2.3.1.192 additional information glycination of phenylacetyl-CoA by human phenacetyltransferase can only be detected at a concentration of glycine above 50 mM, and the rates are below 2% of the rate of glutamination Homo sapiens ?
-
 ?
2.3.1.192 phenylacetyl-CoA + L-glutamine may substitue for glycine, but at lower rate Homo sapiens phenylacetyl-L-glutamine + CoA
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.3.1.192 AAC
-
 Homo sapiens