Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Martinkus, C.; Croteau, R.
    Metabolism of monoterpenes. Evidence for compartmentation of L-menthone metabolism in peppermint (Mentha piperita) leaves (1981), Plant Physiol., 68, 99-106.
    View publication on PubMedView publication on EuropePMC

Activating Compound

EC Number Activating Compound Comment Organism Structure
2.4.1.127 2-mercaptoethanol without addition 73% decrease of activity, suggesting a thiol function necessary for activity Mentha x piperita

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.4.1.127 Ca2+ 5 mM, strong Mentha x piperita
2.4.1.127 CdCl2 strong Mentha x piperita
2.4.1.127 Co2+ 5 mM, strong Mentha x piperita
2.4.1.127 HgCl2 strong Mentha x piperita
2.4.1.127 Ni2+ 5 mM, strong Mentha x piperita
2.4.1.127 p-hydroxymercuribenzoate strong Mentha x piperita
2.4.1.127 Zn2+ 5 mM, strong Mentha x piperita

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.3.1.69 0.24
-
 d-neoisomenthol
-
 Mentha x piperita
2.3.1.69 0.31
-
 d-isomenthol
-
 Mentha x piperita
2.3.1.69 0.32
-
 L-menthol
-
 Mentha x piperita
2.3.1.69 0.35
-
 D-neomenthol
-
 Mentha x piperita
2.4.1.127 0.048
-
 D-neomenthol
-
 Mentha x piperita
2.4.1.127 0.059
-
 L-menthol
-
 Mentha x piperita
2.4.1.127 0.2
-
 UDPglucose reaction with D-neomenthol Mentha x piperita
2.4.1.127 0.25
-
 UDPglucose reaction with L-menthol Mentha x piperita

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
2.4.1.127 Mg2+ 20 mM, about 30% stimulation Mentha x piperita
2.4.1.127 MnCl2 slight stimulation Mentha x piperita

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.4.1.127 46000
-
 gel filtration Mentha x piperita

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.4.1.127 UDPglucose + L-menthol Mentha x piperita enzyme is involved in metabolism of L-menthone UDP + L-menthyl-beta-D-glucoside
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.69 Mentha x piperita
-
 peppermint
-
2.4.1.127 Mentha x piperita
-
 cv. Black Mitcham
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.4.1.127 partial Mentha x piperita

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.3.1.69 leaf midstem leaf of flowering plants Mentha x piperita
-
2.4.1.127 leaf
-
 Mentha x piperita
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.1.69 (+)-isomenthol + acetyl-CoA
-
 Mentha x piperita CoA + (+)-isomenthol acetate
-
 ?
2.3.1.69 (+)-neoisomenthol + acetyl-CoA
-
 Mentha x piperita CoA + (+)-neoisomenthol acetate
-
 ?
2.3.1.69 acetyl-CoA + (+)-neomenthol
-
 Mentha x piperita CoA + neomenthyl acetate
-
 ?
2.3.1.69 acetyl-CoA + (-)-menthol
-
 Mentha x piperita CoA + (-)-menthyl acetate
-
 ?
2.4.1.127 UDPglucose + D-neomenthol
-
 Mentha x piperita UDP + D-neomenthyl-beta-D-glucoside
-
 ?
2.4.1.127 UDPglucose + L-menthol
-
 Mentha x piperita UDP + L-menthyl-beta-D-glucoside
-
 ?
2.4.1.127 UDPglucose + L-menthol enzyme is involved in metabolism of L-menthone Mentha x piperita UDP + L-menthyl-beta-D-glucoside
-
 ?

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.4.1.127 7.3
-
 70 mM Tris-sodium maleate buffer Mentha x piperita
2.4.1.127 7.7
-
 70 mM Na-phosphate buffer Mentha x piperita

pH Range

EC Number pH Minimum pH Maximum Comment Organism
2.4.1.127 6 8.5 about 50% of maximal activity at pH 6.0 and pH 8.5, 70 mM Tris-sodium maleate buffer Mentha x piperita
2.4.1.127 7.3 8.3 about 50% of maximal activity at pH 7.3 and pH 8.3, 70 mM Na-phosphate buffer Mentha x piperita