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Literature summary extracted from

  • Nakano, K.; Takase, C.; Sakamoto, T.; Nakagawa, S.; Inazawa, J.; Ohta, S.; Matuda, S.
    Isolation, characterization and structural organization of the gene and pseudogene for the dihydrolipoamide succinyltransferase component of the human 2-oxoglutarate dehydrogenase complex (1994), Eur. J. Biochem., 224, 179-189.
    View publication on PubMed

Application

EC Number Application Comment Organism
2.3.1.61 medicine possible relationship between enzyme and familial Alzheimer's disease is discussed Homo sapiens

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.3.1.61 isolation of the gene and pseudogene for the dihydrolipoamide succinyltransferase component of the human 2-oxoglutarate dehydrogenase complex from a human genomic DNA library, cloning vector lambda EMBL3 subcloned into plasmid vector pUC18, gene is located on chromosome 14 at q24.2-q24.3, pseudogene is located on chromosome at p31 Homo sapiens

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.3.1.61 mitochondrion
-
 Homo sapiens 5739
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.3.1.61 succinyl-CoA + dihydrolipoamide Homo sapiens
-
 CoA + S-succinyldihydrolipoamide
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.61 Homo sapiens
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.3.1.61 blood peripheral blood cells Homo sapiens
-
2.3.1.61 fibroblast
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.1.61 succinyl-CoA + dihydrolipoamide
-
 Homo sapiens CoA + S-succinyldihydrolipoamide
-
 ?