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Literature summary extracted from

  • Seiler, N.; Al-Therib, J.
    Acetyl-CoA:1,4-diaminobutane N-acetyltransferase. Occurence in vertebrate organs and subcellular localization (1974), Biochim. Biophys. Acta, 354, 206-212.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.3.1.57 acetyl-CoA at high concentrations slight inhibition Rattus norvegicus
2.3.1.57 hexamethylenediamine 30% inhibition Rattus norvegicus
2.3.1.57 mescaline
-
 Rattus norvegicus
2.3.1.57 pentamethylenediamine 30% inhibition Rattus norvegicus
2.3.1.57 SKF 525
-
 Rattus norvegicus
2.3.1.57 spermine
-
 Rattus norvegicus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.3.1.57 3
-
 putrescine
-
 Rattus norvegicus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.3.1.57 microsome
-
 Rattus norvegicus
-
-
2.3.1.57 nucleus
-
 Rattus norvegicus 5634
-

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.57 Rattus norvegicus
-
 Wistar rats, 2 months old
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.3.1.57 brain highest activity Rattus norvegicus
-
2.3.1.57 gut
-
 Rattus norvegicus
-
2.3.1.57 kidney
-
 Rattus norvegicus
-
2.3.1.57 liver
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.1.57 acetyl-CoA + putrescine
-
 Rattus norvegicus CoA + N-acetylputrescine
-
 ?

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
2.3.1.57 37
-
 assay at Rattus norvegicus

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.3.1.57 8
-
-
 Rattus norvegicus