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Literature summary extracted from

  • Hanna, P.E.
    N-acetyltransferases, O-acetyltransferases, and N,O-acetyltransferases: enzymology and bioactivation (1994), Adv. Pharmacol., 27, 401-430.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.3.1.56 1-(fluoren-2-yl)-2-propen-1-one irreversible and selective inactivation Rattus norvegicus
2.3.1.56 N-Hydroxy-2-acetylaminofluorene irreversible, suicide substrate Mesocricetus auratus
2.3.1.56 N-Hydroxy-2-acetylaminofluorene irreversible, suicide substrate Rattus norvegicus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.3.1.56 cytosol
-
 Mus musculus 5829
-
2.3.1.56 cytosol
-
 Homo sapiens 5829
-
2.3.1.56 cytosol
-
 Rattus norvegicus 5829
-
2.3.1.56 cytosol
-
 Oryctolagus cuniculus 5829
-
2.3.1.56 cytosol
-
 Mesocricetus auratus 5829
-

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.56 Homo sapiens
-
-
-
2.3.1.56 Mesocricetus auratus
-
-
-
2.3.1.56 Mus musculus
-
-
-
2.3.1.56 Oryctolagus cuniculus
-
-
-
2.3.1.56 Rattus norvegicus
-
-
-

Reaction

EC Number Reaction Comment Organism Reaction ID
2.3.1.56 N-hydroxy-4-acetylaminobiphenyl + N-hydroxy-4-aminobiphenyl = N-hydroxy-4-aminobiphenyl + N-acetoxy-4-aminobiphenyl mechanism Mus musculus
a
2.3.1.56 N-hydroxy-4-acetylaminobiphenyl + N-hydroxy-4-aminobiphenyl = N-hydroxy-4-aminobiphenyl + N-acetoxy-4-aminobiphenyl mechanism Homo sapiens
a
2.3.1.56 N-hydroxy-4-acetylaminobiphenyl + N-hydroxy-4-aminobiphenyl = N-hydroxy-4-aminobiphenyl + N-acetoxy-4-aminobiphenyl mechanism Rattus norvegicus
a
2.3.1.56 N-hydroxy-4-acetylaminobiphenyl + N-hydroxy-4-aminobiphenyl = N-hydroxy-4-aminobiphenyl + N-acetoxy-4-aminobiphenyl mechanism Oryctolagus cuniculus
a
2.3.1.56 N-hydroxy-4-acetylaminobiphenyl + N-hydroxy-4-aminobiphenyl = N-hydroxy-4-aminobiphenyl + N-acetoxy-4-aminobiphenyl mechanism Mesocricetus auratus
a
2.3.1.56 N-hydroxy-4-acetylaminobiphenyl + N-hydroxy-4-aminobiphenyl = N-hydroxy-4-aminobiphenyl + N-acetoxy-4-aminobiphenyl a single cytosolic protein catalyzes N-acetylation, O-acetylation and N,O-acetylation Mus musculus
a
2.3.1.56 N-hydroxy-4-acetylaminobiphenyl + N-hydroxy-4-aminobiphenyl = N-hydroxy-4-aminobiphenyl + N-acetoxy-4-aminobiphenyl a single cytosolic protein catalyzes N-acetylation, O-acetylation and N,O-acetylation Rattus norvegicus
a
2.3.1.56 N-hydroxy-4-acetylaminobiphenyl + N-hydroxy-4-aminobiphenyl = N-hydroxy-4-aminobiphenyl + N-acetoxy-4-aminobiphenyl a single cytosolic protein catalyzes N-acetylation, O-acetylation and N,O-acetylation Oryctolagus cuniculus
a
2.3.1.56 N-hydroxy-4-acetylaminobiphenyl + N-hydroxy-4-aminobiphenyl = N-hydroxy-4-aminobiphenyl + N-acetoxy-4-aminobiphenyl a single cytosolic protein catalyzes N-acetylation, O-acetylation and N,O-acetylation Mesocricetus auratus
a

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.3.1.56 colon
-
 Homo sapiens
-
2.3.1.56 colon
-
 Rattus norvegicus
-
2.3.1.56 colon
-
 Mesocricetus auratus
-
2.3.1.56 intestine
-
 Rattus norvegicus
-
2.3.1.56 intestine
-
 Mesocricetus auratus
-
2.3.1.56 liver
-
 Mus musculus
-
2.3.1.56 liver
-
 Homo sapiens
-
2.3.1.56 liver
-
 Rattus norvegicus
-
2.3.1.56 liver
-
 Oryctolagus cuniculus
-
2.3.1.56 liver
-
 Mesocricetus auratus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.1.56 N-hydroxy-2-acetylaminofluorene + N-hydroxy-4-aminobiphenyl
-
 Homo sapiens N-hydroxy-2-aminofluorene + N-acetoxy-4-aminobiphenyl
-
 ?
2.3.1.56 N-hydroxy-2-acetylaminofluorene + N-hydroxy-4-aminobiphenyl
-
 Rattus norvegicus N-hydroxy-2-aminofluorene + N-acetoxy-4-aminobiphenyl
-
 ?
2.3.1.56 N-hydroxy-2-acetylaminofluorene + N-hydroxy-4-aminobiphenyl
-
 Mesocricetus auratus N-hydroxy-2-aminofluorene + N-acetoxy-4-aminobiphenyl
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.3.1.56 More monomorphic enzyme Rattus norvegicus
2.3.1.56 More monomorphic enzyme Mesocricetus auratus