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Literature summary extracted from

  • Sticha, K.R.K.; Bergstrom, C.P.; Wagner, C.R.; Hanna, P.E.
    Characterization of hamster recombinant monomorphic and polymorphic arylamine N-acetyltransferases. Bioactivation and mechanism-based inactivation studies with N-hydroxy-2-acetylaminofluorene (1998), Biochem. Pharmacol., 56, 47-59.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.3.1.5 N-Hydroxy-2-acetylaminofluorene mechanism-based inactivator, kinetics Mesocricetus auratus

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.5 Mesocricetus auratus
-
 recombinant NAT1, NAT2
-

Reaction

EC Number Reaction Comment Organism Reaction ID
2.3.1.5 acetyl-CoA + an arylamine = CoA + an N-acetylarylamine mechanism and inactivation Mesocricetus auratus
a

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.1.5 N-hydroxy-2-acetylaminofluorene + 4-aminoazobenzene much better acetyl donor for NAT1 than for NAT2 Mesocricetus auratus CoA + ?
-
 ?