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Literature summary extracted from

  • Krimbou, L.; Marcil, M.; Davignon, J.; Genest, J.Jr.
    Interaction of lecithin:cholesterol acyltransferase (LCAT).a2-macroglobulin complex with low density lipoprotein receptor-related protein (LRP). Evidence for an a2-macroglobulin/LRP receptor-mediated system participating in LCAT clearance (2001), J. Biol. Chem., 276, 33241-33248.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.3.1.43 alpha2-Macroglobulin association of this protein with LCAT inhibits the activity of LCAT, and may have a role in its catabolism Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.43 Homo sapiens
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Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.1.43 phosphatidylcholine + sterol
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Homo sapiens 1-acylglycerophosphocholine + sterol ester
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