Literature summary extracted from
Knipping, G.
Isolation and properties of porcine lecithin:cholesterol acyltransferase (1986), Eur. J. Biochem., 154, 289-294.
Activating Compound
EC Number |
Activating Compound |
Comment |
Organism |
Structure |
---|
2.3.1.43 |
apolipoprotein A-I |
both human and pig ApoA-1 can activate pig LCAT in cholesterol-lecithin liposomes |
Sus scrofa |
|
Inhibitors
EC Number |
Inhibitors |
Comment |
Organism |
Structure |
---|
2.3.1.43 |
apolipoprotein C-2 |
inhibitor in high concentration |
Sus scrofa |
|
Molecular Weight [Da]
EC Number |
Molecular Weight [Da] |
Molecular Weight Maximum [Da] |
Comment |
Organism |
---|
2.3.1.43 |
69000 |
- |
x * 69000, SDS-PAGE |
Sus scrofa |
Organism
EC Number |
Organism |
UniProt |
Comment |
Textmining |
---|
2.3.1.43 |
Sus scrofa |
- |
pig |
- |
Posttranslational Modification
EC Number |
Posttranslational Modification |
Comment |
Organism |
---|
2.3.1.43 |
glycoprotein |
21% w/w carbohydrate, including hexoses, hexosamines and sialic acids |
Sus scrofa |
Purification (Commentary)
EC Number |
Purification (Comment) |
Organism |
---|
2.3.1.43 |
phenyl-Sepharose and hydroxyapatite column chromatography |
Sus scrofa |
Source Tissue
EC Number |
Source Tissue |
Comment |
Organism |
Textmining |
---|
2.3.1.43 |
plasma |
- |
Sus scrofa |
- |
Specific Activity [micromol/min/mg]
EC Number |
Specific Activity Minimum [µmol/min/mg] |
Specific Activity Maximum [µmol/min/mg] |
Comment |
Organism |
---|
2.3.1.43 |
0.15 |
- |
in cholesterol-lecithin vesicles activated with porcine apolipoprotein A1 |
Sus scrofa |
Substrates and Products (Substrate)
EC Number |
Substrates |
Comment Substrates |
Organism |
Products |
Comment (Products) |
Rev. |
Reac. |
---|
2.3.1.43 |
additional information |
lecithin-cholesterol single bilayer vesicles as substrate |
Sus scrofa |
? |
- |
? |
|
2.3.1.43 |
phosphatidylcholine + sterol |
- |
Sus scrofa |
1-acylglycerophosphocholine + sterol ester |
- |
r |
|
Subunits
EC Number |
Subunits |
Comment |
Organism |
---|
2.3.1.43 |
? |
x * 69000, SDS-PAGE |
Sus scrofa |