Literature summary extracted from

Jauhiainen, M.; Yuan, W.; Gelb, M.H.; Dolphin, P.J.
Human plasma lecithin-cholesterol acyltransferase. Inhibition of the phospholipase A2-like activity by sn-2-difluoroketone phosphatidylcholine analogues (1989), J. Biol. Chem., 264, 1963-1967.

Inhibitors

EC Number	Inhibitors	Comment	Organism	Structure
2.3.1.43	Sn-2-Difluoroketone phosphatidylcholine analogues	IC50 values between 0.5 and 0.028 mM	Homo sapiens

Organism

EC Number	Organism	UniProt	Comment	Textmining
2.3.1.43	Homo sapiens	-	-	-

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
2.3.1.43	plasma	-	Homo sapiens	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
2.3.1.43	phosphatidylcholine + sterol	cholesterol as substrate	Homo sapiens	1-acylglycerophosphocholine + sterol ester	-	r

IC50 Value

EC Number	IC50 Value	IC50 Value Maximum	Comment	Organism	Inhibitor	Structure
2.3.1.43	0.5	0.028	IC50 values between 0.5 and 0.028 mM	Homo sapiens	Sn-2-Difluoroketone phosphatidylcholine analogues

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Release 2023.1 (January 2023)