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Literature summary extracted from

  • Worsham, L.M.S.; Williams, S.G.; Ernst-Fonberg, M.L.
    Early catalytic steps of Euglena gracilis chloroplast type II fatty acid synthase (1993), Biochim. Biophys. Acta, 1170, 62-71.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.3.1.38 iodoacetamide no inhibition Euglena gracilis
2.3.1.38 additional information no inhibition by diisopropylphosphofluoridate and antibiotic cerulenin Euglena gracilis
2.3.1.38 N-ethylmaleimide weak Euglena gracilis
2.3.1.38 p-chloromercuribenzoate strong inhibition Euglena gracilis
2.3.1.86 cerulenin complete inhibition of type II fatty acid synthase at 0.1 mM Euglena gracilis
2.3.1.86 iodoacetamide complete inhibition of type II fatty acid synthase at 1 mM Euglena gracilis
2.3.1.86 N-ethylmaleimide complete inhibition of type II fatty acid synthase at 1 mM Euglena gracilis
2.3.1.86 p-chloromercuribenzoate complete inhibition of type II fatty acid synthase at 1 mM Euglena gracilis

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.3.1.38 chloroplast fatty acid synthase II Euglena gracilis 9507
-
2.3.1.38 cytosol fatty acid synthase II Euglena gracilis 5829
-

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.3.1.38 60000
-
 gel filtration Euglena gracilis
2.3.1.86 additional information
-
 MW of components Euglena gracilis

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.3.1.38 acetyl-CoA + [acyl-carrier protein] Euglena gracilis enzyme is component of fatty acid synthase complex II CoA + acetyl-[acyl-carrier protein]
-
 ?
2.3.1.38 acetyl-CoA + [acyl-carrier protein] Euglena gracilis first step of fatty acid synthesis CoA + acetyl-[acyl-carrier protein]
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.38 Euglena gracilis
-
 v. bacillaris
-
2.3.1.86 Euglena gracilis
-
 var. bacillaris
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.3.1.38 partial Euglena gracilis
2.3.1.86 partial purification of components Euglena gracilis

Source Tissue

EC Number Source Tissue Comment Organism Textmining

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
2.3.1.38 0.03
-
 partially purified enzyme Euglena gracilis

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.1.38 acetyl-CoA + [acyl-carrier protein]
-
 Euglena gracilis CoA + acetyl-[acyl-carrier protein]
-
 ?
2.3.1.38 acetyl-CoA + [acyl-carrier protein] enzyme is component of fatty acid synthase complex II Euglena gracilis CoA + acetyl-[acyl-carrier protein]
-
 ?
2.3.1.38 acetyl-CoA + [acyl-carrier protein] first step of fatty acid synthesis Euglena gracilis CoA + acetyl-[acyl-carrier protein]
-
 ?

Subunits

EC Number Subunits Comment Organism
2.3.1.86 More two de novo fatty acid synthases, a true multienzyme complex in the cytosol and a plastid-localized type II fatty acid synthase composed of discrete enzymes and acyl carrier protein Euglena gracilis

Synonyms

EC Number Synonyms Comment Organism
2.3.1.38 acetyl-CoA-ACP-transacylase
-
 Euglena gracilis

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
2.3.1.38 35
-
 assay at Euglena gracilis

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.3.1.38 8
-
 assay at Euglena gracilis