EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
2.3.1.37 | divalent cations | Mg2+ or Ca2+: optimal at concentration of 50 mM, inhibition above 200 mM | Gallus gallus | |
2.3.1.37 | hemin | - |
Gallus gallus | |
2.3.1.37 | monovalent cations | Na+ or Li+: optimal at 0.5 M, not inhibitory up to 1 M | Gallus gallus | |
2.3.1.37 | p-chloromercuribenzoate | - |
Gallus gallus |
EC Number | Metals/Ions | Comment | Organism | Structure |
---|---|---|---|---|
2.3.1.37 | Ca2+ | optimal at concentration of 50 mM, inhibition above 200 mM | Gallus gallus | |
2.3.1.37 | Li+ | optimal at 0.5 M, not inhibitory up to 1 M | Gallus gallus | |
2.3.1.37 | Li+ | in Mg2+-containing medium: at 100 mM no effect on activity, higher concentrations are totally inhibitory | Gallus gallus | |
2.3.1.37 | Mg2+ | optimal at concentration of 50 mM, inhibition above 200 mM | Gallus gallus | |
2.3.1.37 | Na+ | optimal at 0.5 M, not inhibitory up to 1 M | Gallus gallus | |
2.3.1.37 | Na+ | in Mg2+-containing medium: at 100 mM no effect on activity, higher concentrations are totally inhibitory | Gallus gallus |
EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|---|
2.3.1.37 | 49000 | - |
2 * 49000, SDS-PAGE | Gallus gallus |
2.3.1.37 | 87000 | - |
gel filtration | Gallus gallus |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.3.1.37 | Gallus gallus | - |
- |
- |
EC Number | Purification (Comment) | Organism |
---|---|---|
2.3.1.37 | - |
Gallus gallus |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
2.3.1.37 | embryo | - |
Gallus gallus | - |
2.3.1.37 | liver | fetal | Gallus gallus | - |
EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|---|
2.3.1.37 | additional information | - |
- |
Gallus gallus |
EC Number | Storage Stability | Organism |
---|---|---|
2.3.1.37 | -15°C, 20 mM potassium phosphate buffer, pH 7.6, 1 mM dithioerythritol, 0.01 mM pyridoxal 5'-phosphate, 30% loss of activity after 2 weeks | Gallus gallus |
2.3.1.37 | 4°C, 20 mM potassium phosphate buffer, pH 7.6, 1 mM dithioerythritol, 0.01 mM pyridoxal 5'-phosphate, 20% loss of activity after 2 weeks | Gallus gallus |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.3.1.37 | succinyl-CoA + glycine | - |
Gallus gallus | 5-aminolevulinate + CoA + CO2 | - |
? |
EC Number | Subunits | Comment | Organism |
---|---|---|---|
2.3.1.37 | dimer | 2 * 49000, SDS-PAGE | Gallus gallus |
EC Number | Cofactor | Comment | Organism | Structure |
---|---|---|---|---|
2.3.1.37 | pyridoxal 5'-phosphate | required | Gallus gallus |
EC Number | Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|---|
2.3.1.37 | 0.035 | - |
hemin | - |
Gallus gallus |