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Literature summary extracted from

  • Kredich, N.M.; Becker, M.A.
    Cysteine biosynthesis: serine transacetylase and O-acetylserine sulfhydrylase (Salmonella typhimurium) (1971), Methods Enzymol., 17, 459-470.
No PubMed abstract available

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.3.1.30 L-cysteine
-
 Escherichia coli
2.3.1.30 L-cysteine
-
 Salmonella enterica subsp. enterica serovar Typhimurium

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.3.1.30 0.12
-
 acetyl-CoA
-
 Salmonella enterica subsp. enterica serovar Typhimurium
2.3.1.30 0.7
-
 L-serine
-
 Salmonella enterica subsp. enterica serovar Typhimurium

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.3.1.30 acetyl-CoA + L-serine Salmonella enterica subsp. enterica serovar Typhimurium first enzyme in L-cysteine synthesis pathway CoA + O-acetyl-L-serine
-
 ir
2.3.1.30 acetyl-CoA + L-serine Escherichia coli first enzyme in L-cysteine synthesis pathway CoA + O-acetyl-L-serine
-
 ir

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.30 Escherichia coli
-
-
-
2.3.1.30 Salmonella enterica subsp. enterica serovar Typhimurium
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.3.1.30
-
 Salmonella enterica subsp. enterica serovar Typhimurium

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
2.3.1.30 additional information
-
-
 Salmonella enterica subsp. enterica serovar Typhimurium
2.3.1.30 additional information
-
-
 Escherichia coli
2.3.1.30 114
-
 purified enzyme Salmonella enterica subsp. enterica serovar Typhimurium

Storage Stability

EC Number Storage Stability Organism
2.3.1.30 -20°C, stable for months Salmonella enterica subsp. enterica serovar Typhimurium
2.3.1.30 4°C, unstable Salmonella enterica subsp. enterica serovar Typhimurium

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.1.30 acetyl-CoA + L-serine
-
 Salmonella enterica subsp. enterica serovar Typhimurium CoA + O-acetyl-L-serine
-
 ir
2.3.1.30 acetyl-CoA + L-serine
-
 Escherichia coli CoA + O-acetyl-L-serine
-
 ir
2.3.1.30 acetyl-CoA + L-serine first enzyme in L-cysteine synthesis pathway Salmonella enterica subsp. enterica serovar Typhimurium CoA + O-acetyl-L-serine
-
 ir
2.3.1.30 acetyl-CoA + L-serine first enzyme in L-cysteine synthesis pathway Escherichia coli CoA + O-acetyl-L-serine
-
 ir