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Literature summary extracted from

  • Akermoun, M.; Testet, E.; Cassagne, C.; Bessoule, J.J.
    Inhibition of the plastidial phosphatidylcholine synthesis by silver, copper, lead and mercury induced by formation of mercaptides with the lyso-PC acyltransferase (2002), Biochim. Biophys. Acta, 1581, 21-28.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.3.1.23 Ag+ 0.000005 mM, almost complete inhibition, noncompetitive, irreversible, probably due to formation of a thiolate Allium ampeloprasum
2.3.1.23 Cu2+ 0.00001 mM, 50% inhibition, noncompetitive, irreversible, probably due to formation of a thiolate Allium ampeloprasum
2.3.1.23 Hg2+ 0.00001 mM, 50% inhibition, noncompetitive, irreversible, probably due to formation of a thiolate Allium ampeloprasum
2.3.1.23 Pb2+ 0.00002 mM, 50% inhibition, noncompetitive, irreversible, probably due to formation of a thiolate Allium ampeloprasum

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.3.1.23 0.026
-
 oleoyl-CoA
-
 Allium ampeloprasum
2.3.1.23 0.032
-
 1-acyl-sn-glycero-3-phosphocholine
-
 Allium ampeloprasum

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.23 Allium ampeloprasum
-
 leek
-
2.3.1.23 Helianthus annuus
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.1.23 acyl-CoA + 1-acyl-sn-glycero-3-phosphocholine
-
 Allium ampeloprasum CoA + 1,2-diacyl-sn-glycero-3-phosphocholine
-
 r
2.3.1.23 acyl-CoA + 1-acyl-sn-glycero-3-phosphocholine
-
 Helianthus annuus CoA + 1,2-diacyl-sn-glycero-3-phosphocholine
-
 r
2.3.1.23 oleoyl-CoA + 1-oleoyl-sn-glycero-3-phosphocholine
-
 Allium ampeloprasum CoA + 1,2-dioleoyl-sn-glycero-3-phosphocholine
-
 ?