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Literature summary extracted from

  • Clarke, P.R.H.; Bieber, L.L.
    Isolation and purification of mitochondrial carnitine octanoyltransferase activities from beef heart (1981), J. Biol. Chem., 256, 9861-9868.
    View publication on PubMed

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.3.1.21 mitochondrion
-
 Bos taurus 5739
-

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.3.1.21 additional information
-
 enzyme migrates as part of a detergent micelle with MW of 510000 on gel filtration Bos taurus
2.3.1.21 67000
-
 x * 67000, SDS-PAGE Bos taurus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.3.1.21 acyl-CoA + L-carnitine Bos taurus
-
 CoA + L-acylcarnitine
-
 r

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.21 Bos taurus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.3.1.21
-
 Bos taurus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.3.1.21 heart
-
 Bos taurus
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
2.3.1.21 47.5
-
 purified enzyme Bos taurus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.1.21 acyl-CoA + L-carnitine
-
 Bos taurus CoA + L-acylcarnitine
-
 r
2.3.1.21 decanoyl-CoA + L-carnitine best substrate Bos taurus CoA + L-decanoylcarnitine
-
 r
2.3.1.21 hexanoyl-CoA + L-carnitine
-
 Bos taurus CoA + L-hexanoylcarnitine
-
 r
2.3.1.21 lauroyl-CoA + L-carnitine best substrate Bos taurus CoA + L-lauroylcarnitine
-
 r
2.3.1.21 myristoyl-CoA + L-carnitine
-
 Bos taurus CoA + L-myristoylcarnitine
-
 ?
2.3.1.21 octanoyl-CoA + L-carnitine
-
 Bos taurus CoA + L-octanoylcarnitine
-
 r
2.3.1.21 palmitoyl-CoA + L-carnitine
-
 Bos taurus CoA + L-palmitoylcarnitine
-
 r

Subunits

EC Number Subunits Comment Organism
2.3.1.21 ? x * 67000, SDS-PAGE Bos taurus

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
2.3.1.21 25
-
 assay at Bos taurus

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.3.1.21 additional information
-
 pI: 8.5 Bos taurus
2.3.1.21 8
-
 assay at Bos taurus