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Literature summary extracted from

  • Yamashita, S.; Hosaka, K.; Miki, Y.; Numa, S.
    Glycerolipid acyltransferases from rat liver: 1-acylglycerophosphate acyltransferase, 1-acylglycerophosphorylcholine acyltransferase, and diacylglycerol acyltransferase (1981), Methods Enzymol., 71, 528-536.
    View publication on PubMed

General Stability

EC Number General Stability Organism
2.3.1.51 ethylene glycol, 20% v/v, stabilizes Rattus norvegicus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.3.1.20 microsome
-
 Rattus norvegicus
-
-
2.3.1.23 microsome
-
 Rattus norvegicus
-
-
2.3.1.51 microsome
-
 Rattus norvegicus
-
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.3.1.51 acyl-CoA + 1-acyl-sn-glycerol 3-phosphate Rattus norvegicus involved in phospholipid biosynthesis CoA + 1,2-diacyl-sn-glycerol 3-phosphate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.20 Rattus norvegicus
-
-
-
2.3.1.23 Rattus norvegicus
-
-
-
2.3.1.51 Rattus norvegicus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.3.1.20 partial Rattus norvegicus
2.3.1.23 partially purified Rattus norvegicus
2.3.1.23 solubilized with Triton X-100 Rattus norvegicus
2.3.1.51 partial Rattus norvegicus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.3.1.20 liver
-
 Rattus norvegicus
-
2.3.1.23 liver
-
 Rattus norvegicus
-
2.3.1.51 liver
-
 Rattus norvegicus
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
2.3.1.20 0.0089
-
-
 Rattus norvegicus
2.3.1.23 0.68
-
 acyl donor arachidonoyl-CoA Rattus norvegicus
2.3.1.51 0.44
-
-
 Rattus norvegicus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.1.20 acyl-CoA + 1,2-diacylglycerol acyl-donors: broad specificity, saturated, mono-, di- and tetraenoic thioesters Rattus norvegicus CoA + triacylglycerol
-
 ?
2.3.1.23 acyl-CoA + 1-acyl-sn-glycero-3-phosphocholine
-
 Rattus norvegicus CoA + 1,2-diacyl-sn-glycero-3-phosphocholine
-
 r
2.3.1.51 acyl-CoA + 1-acyl-sn-glycerol 3-phosphate monoenic and dienic acyl-CoA thioesters Rattus norvegicus CoA + 1,2-diacyl-sn-glycerol 3-phosphate i.e. phosphatidic acid ?
2.3.1.51 acyl-CoA + 1-acyl-sn-glycerol 3-phosphate involved in phospholipid biosynthesis Rattus norvegicus CoA + 1,2-diacyl-sn-glycerol 3-phosphate
-
 ?
2.3.1.51 acyl-CoA + 1-arachidonoyl-sn-glycerol 3-phosphate less efficient than 1-acyl-sn-glycerol 3-phosphate Rattus norvegicus CoA + 1-arachidonoyl-2-acyl-sn-glycerol 3-phosphate
-
 ?
2.3.1.51 acyl-CoA + 1-stearoyl-sn-glycerol 3-phosphate less efficient than 1-acyl-sn-glycerol 3-phosphate Rattus norvegicus CoA + 1-stearoyl-2-acyl-sn-glycerol 3-phosphate
-
 ?
2.3.1.51 arachidonoyl-CoA + 1-acyl-sn-glycerol 3-phosphate arachidonoyl-CoA is a poor substrate Rattus norvegicus CoA + 1-acyl-2-arachidonoyl-sn-glycerol 3-phosphate
-
 ?
2.3.1.51 lauroyl-CoA + 1-acyl-sn-glycerol 3-phosphate lauroyl-CoA is a poor substrate Rattus norvegicus CoA + 1-acyl-2-lauroyl-sn-glycerol 3-phosphate
-
 ?
2.3.1.51 linoleoyl-CoA + 1-acyl-sn-glycerol 3-phosphate
-
 Rattus norvegicus CoA + 1-acyl-2-linoleoyl-sn-glycerol 3-phosphate
-
 ?
2.3.1.51 myristoyl-CoA + 1-acyl-sn-glycerol 3-phosphate myristoyl-CoA is a poor substrate Rattus norvegicus CoA + 1-acyl-2-myristoyl-sn-glycerol 3-phosphate
-
 ?
2.3.1.51 oleoyl-CoA + 1-acyl-sn-glycerol 3-phosphate
-
 Rattus norvegicus CoA + 1-acyl-2-oleoyl-sn-glycerol 3-phosphate
-
 ?
2.3.1.51 palmitoleoyl-CoA + 1-acyl-sn-glycerol 3-phosphate
-
 Rattus norvegicus CoA + 1-acyl-2-palmitoleoyl-sn-glycerol 3-phosphate
-
 ?
2.3.1.51 palmitoyl-CoA + 1-acyl-sn-glycerol 3-phosphate
-
 Rattus norvegicus CoA + 1-acyl-2-palmitoyl-sn-glycerol 3-phosphate
-
 ?
2.3.1.51 stearoyl-CoA + 1-acyl-sn-glycerol 3-phosphate stearoyl-CoA is a poor substrate Rattus norvegicus CoA + 1-acyl-2-stearoyl-sn-glycerol 3-phosphate
-
 ?

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
2.3.1.20 additional information
-
 assay at various temperatures from 24°C to 40°C Rattus norvegicus
2.3.1.20 27
-
 assay at Rattus norvegicus
2.3.1.23 37
-
-
 Rattus norvegicus
2.3.1.51 37
-
 assay at Rattus norvegicus