Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Staack, H.; Binstock, J.F.; Schulz, H.
    Purification and properties of a pig heart thiolase with broad chain length specificity and comparison of thiolases from pig heart and Escherichia coli (1978), J. Biol. Chem., 253, 1827-1831.
    View publication on PubMed

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.3.1.16 additional information
-
 additional information
-
 Sus scrofa
2.3.1.16 0.0018
-
 3-oxodecanoyl-CoA
-
 Sus scrofa
2.3.1.16 0.0024
-
 3-oxooctanoyl-CoA
-
 Sus scrofa
2.3.1.16 0.0083
-
 3-oxohexanoyl-CoA
-
 Sus scrofa
2.3.1.16 0.016
-
 acetoacetyl-CoA
-
 Sus scrofa

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.3.1.16 46000
-
 4 * 46000, SDS-PAGE Sus scrofa
2.3.1.16 200000
-
 gel filtration Sus scrofa

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.3.1.16 CoA + 3-oxoacyl-CoA Sus scrofa
-
 acyl-CoA + acetyl-CoA
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.16 Sus scrofa
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.3.1.16
-
 Sus scrofa

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.3.1.16 heart muscle Sus scrofa
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
2.3.1.16 597
-
-
 Sus scrofa

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.1.16 CoA + 3-oxoacyl-CoA
-
 Sus scrofa acyl-CoA + acetyl-CoA
-
 ?
2.3.1.16 CoA + 3-oxodecanoyl-CoA
-
 Sus scrofa acetyl-CoA + octanoyl-CoA
-
 ?
2.3.1.16 CoA + 3-oxohexanoyl-CoA
-
 Sus scrofa acetyl-CoA + butanoyl-CoA
-
 ?
2.3.1.16 CoA + 3-oxooctanoyl-CoA
-
 Sus scrofa acetyl-CoA + hexanoyl-CoA
-
 ?
2.3.1.16 CoA + acetoacetyl-CoA
-
 Sus scrofa acetyl-CoA + acetyl-CoA
-
 ?

Subunits

EC Number Subunits Comment Organism
2.3.1.16 tetramer 4 * 46000, SDS-PAGE Sus scrofa