Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Kume, K.; Shimizu, T.; Seyama, Y.
    Characterization of sn-glycerol 3-phosphate acyltransferase from guinea pig harderian gland microsomes (1987), J. Biochem., 101, 653-660.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
2.3.1.15 bovine serum albumin alleviates detergent effect of palmitoyl-CoA Cavia porcellus

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.3.1.15 2-mercaptoethanol
-
 Cavia porcellus
2.3.1.15 5,5'-dithiobis(2-nitro-benzoate) 1 mM, 20-30% inhibition of activity on palmitoyl-CoA, complete inhibition of activity on other acyl-CoAs Cavia porcellus
2.3.1.15 dihydroxyacetone phosphate palmitoyl-CoA-specific isozyme Cavia porcellus
2.3.1.15 dithiothreitol palmitoyl-CoA-specific isozyme Cavia porcellus
2.3.1.15 N-ethylmaleimide
-
 Cavia porcellus
2.3.1.15 p-chloromercuribenzoate
-
 Cavia porcellus
2.3.1.15 palmitoyl-CoA bovine serum albumin attenuates Cavia porcellus
2.3.1.15 Triton X-100
-
 Cavia porcellus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.3.1.15 0.5
-
 sn-glycerol 3-phosphate assay with microsomal preparation Cavia porcellus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.3.1.15 microsome
-
 Cavia porcellus
-
-
2.3.1.15 mitochondrion DTNB-resistant isozyme Cavia porcellus 5739
-

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.15 Cavia porcellus
-
 Hartley strain, female
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.3.1.15 harderian gland
-
 Cavia porcellus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.1.15 acyl-CoA + sn-glycerol 3-phosphate
-
 Cavia porcellus CoA + 1-acyl-sn-glycerol 3-phosphate
-
 ?
2.3.1.15 arachidonoyl-CoA + sn-glycerol 3-phosphate 20% of the reaction rate with palmitoyl-CoA Cavia porcellus CoA + 1-arachidonoyl-sn-glycerol 3-phosphate
-
 ?
2.3.1.15 linoleoyl-CoA + sn-glycerol 3-phosphate 40% of the reaction rate with palmitoyl-CoA Cavia porcellus CoA + 1-linoleoyl-sn-glycerol 3-phosphate
-
 ?
2.3.1.15 linoleoyl-CoA + sn-glycerol 3-phosphate no substrate for DTNB-resistant isozyme Cavia porcellus CoA + 1-linoleoyl-sn-glycerol 3-phosphate
-
 ?
2.3.1.15 oleoyl-CoA + sn-glycerol 3-phosphate 50% of the reaction rate with palmitoyl-CoA Cavia porcellus CoA + 1-oleoyl-sn-glycerol 3-phosphate
-
 ?
2.3.1.15 palmitoyl-CoA + sn-glycerol 3-phosphate i.e. n-hexadecanoyl-CoA, best substrate Cavia porcellus CoA + 1-palmitoyl-sn-glycerol 3-phosphate
-
 ?
2.3.1.15 stearoyl-CoA + sn-glycerol 3-phosphate i.e. n-octadecanoyl-CoA, 30% of the reaction rate with palmitoyl-CoA Cavia porcellus CoA + 1-stearoyl-sn-glycerol 3-phosphate
-
 ?