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Literature summary extracted from

  • Pomper, B.K.; Saurel, O.; Milon, A.; Vorholt, J.A.
    Generation of formate by the formyltransferase/hydrolase complex (Fhc) from Methylobacterium extorquens AM1 (2002), FEBS Lett., 523, 133-137.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.3.1.101 formylmethanofuran + 5,6,7,8-tetrahydromethanopterin Methylorubrum extorquens
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methanofuran + N5-formyl-5,6,7,8-tetrahydromethanopterin
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r

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.101 Methylorubrum extorquens
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Reaction

EC Number Reaction Comment Organism Reaction ID
2.3.1.101 formylmethanofuran + 5,6,7,8-tetrahydromethanopterin = methanofuran + 5-formyl-5,6,7,8-tetrahydromethanopterin enzyme complex renamed formyltransferase/hydrolase complex Methylorubrum extorquens
2.3.1.101 formylmethanofuran + 5,6,7,8-tetrahydromethanopterin = methanofuran + 5-formyl-5,6,7,8-tetrahydromethanopterin pathway via enzyme complex Methylorubrum extorquens

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.1.101 formylmethanofuran + 5,6,7,8-tetrahydromethanopterin
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Methylorubrum extorquens methanofuran + N5-formyl-5,6,7,8-tetrahydromethanopterin
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r
2.3.1.101 additional information formyltransferase/hydrolase complex also catalyzes the hydrolysis of formyl-methanofuran to formate Methylorubrum extorquens ?
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