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Literature summary extracted from

  • Schenk, G.; Duggleby, R.G.; Nixon, P.F.
    Properties and functions of the thiamin diphosphate dependent enzyme transketolase (1998), Int. J. Biochem. Cell Biol., 30, 1297-1318.
    View publication on PubMed

General Stability

EC Number General Stability Organism
2.2.1.1 freezing and thawing causes loss of activity Homo sapiens

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.2.1.1 0.09
-
D-erythrose 4-phosphate
-
Escherichia coli
2.2.1.1 0.16
-
D-xylulose 5-phosphate
-
Escherichia coli
2.2.1.1 0.21
-
D-xylulose 5-phosphate
-
Saccharomyces cerevisiae
2.2.1.1 0.36
-
D-erythrose 4-phosphate
-
Homo sapiens
2.2.1.1 0.4
-
D-ribose 5-phosphate
-
Spinacia oleracea
2.2.1.1 0.4
-
D-ribose 5-phosphate
-
Saccharomyces cerevisiae
2.2.1.1 0.49
-
D-xylulose 5-phosphate
-
Homo sapiens
2.2.1.1 0.53
-
D-ribose 5-phosphate
-
Homo sapiens
2.2.1.1 1.1
-
fructose 6-phosphate
-
Escherichia coli
2.2.1.1 1.4
-
D-ribose 5-phosphate
-
Escherichia coli
2.2.1.1 1.8
-
fructose 6-phosphate
-
Saccharomyces cerevisiae
2.2.1.1 2.1
-
D,L-glyceraldehyde 3-phosphate
-
Escherichia coli
2.2.1.1 3.2
-
fructose 6-phosphate
-
Spinacia oleracea
2.2.1.1 4.9
-
glyceraldehyde 3-phosphate
-
Saccharomyces cerevisiae
2.2.1.1 7
-
fructose 6-phosphate
-
Homo sapiens
2.2.1.1 18
-
Hydroxypyruvate
-
Escherichia coli
2.2.1.1 33
-
Hydroxypyruvate
-
Saccharomyces cerevisiae
2.2.1.1 45
-
D-xylose
-
Spinacia oleracea
2.2.1.1 55
-
L-arabinose
-
Spinacia oleracea
2.2.1.1 120
-
L-Lyxose
-
Spinacia oleracea
2.2.1.1 230
-
D-ribose
-
Spinacia oleracea

Organism

EC Number Organism UniProt Comment Textmining
2.2.1.1 Cyberlindnera jadinii
-
-
-
2.2.1.1 Escherichia coli
-
-
-
2.2.1.1 Homo sapiens
-
-
-
2.2.1.1 Mus musculus
-
-
-
2.2.1.1 Oryctolagus cuniculus
-
-
-
2.2.1.1 Rattus norvegicus
-
-
-
2.2.1.1 Saccharomyces cerevisiae P23254 baker's yeast
-
2.2.1.1 Saccharomyces pastorianus
-
-
-
2.2.1.1 Spinacia oleracea
-
spinach
-
2.2.1.1 Sus scrofa
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.2.1.1 brain
-
Mus musculus
-
2.2.1.1 erythrocyte
-
Homo sapiens
-
2.2.1.1 leukocyte
-
Homo sapiens
-
2.2.1.1 liver
-
Rattus norvegicus
-
2.2.1.1 liver
-
Sus scrofa
-
2.2.1.1 liver
-
Oryctolagus cuniculus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.2.1.1 D-erythrose 4-phosphate + ?
-
Escherichia coli ?
-
?
2.2.1.1 D-erythrose 4-phosphate + ?
-
Homo sapiens ?
-
?
2.2.1.1 D-ribose + ?
-
Spinacia oleracea ?
-
?
2.2.1.1 D-xylose + ?
-
Spinacia oleracea ?
-
?
2.2.1.1 D-xylulose 5-phosphate + D-ribose 5-phosphate
-
Saccharomyces pastorianus sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate
-
r
2.2.1.1 D-xylulose 5-phosphate + D-ribose 5-phosphate
-
Cyberlindnera jadinii sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate
-
r
2.2.1.1 D-xylulose 5-phosphate + D-ribose 5-phosphate
-
Escherichia coli sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate
-
r
2.2.1.1 D-xylulose 5-phosphate + D-ribose 5-phosphate
-
Homo sapiens sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate
-
r
2.2.1.1 D-xylulose 5-phosphate + D-ribose 5-phosphate
-
Rattus norvegicus sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate
-
r
2.2.1.1 D-xylulose 5-phosphate + D-ribose 5-phosphate
-
Sus scrofa sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate
-
r
2.2.1.1 D-xylulose 5-phosphate + D-ribose 5-phosphate
-
Oryctolagus cuniculus sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate
-
r
2.2.1.1 D-xylulose 5-phosphate + D-ribose 5-phosphate
-
Spinacia oleracea sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate
-
r
2.2.1.1 D-xylulose 5-phosphate + D-ribose 5-phosphate
-
Saccharomyces cerevisiae sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate
-
r
2.2.1.1 DL-glyceraldehyde 3-phosphate + ?
-
Escherichia coli ?
-
?
2.2.1.1 DL-glyceraldehyde 3-phosphate + ?
-
Saccharomyces cerevisiae ?
-
?
2.2.1.1 fructose 6-phosphate + ?
-
Escherichia coli ?
-
?
2.2.1.1 fructose 6-phosphate + ?
-
Homo sapiens ?
-
?
2.2.1.1 fructose 6-phosphate + ?
-
Spinacia oleracea ?
-
?
2.2.1.1 fructose 6-phosphate + ?
-
Saccharomyces cerevisiae ?
-
?
2.2.1.1 hydroxypyruvate + ribose 5-phosphate
-
Escherichia coli sedoheptulose 7-phosphate + ?
-
?
2.2.1.1 hydroxypyruvate + ribose 5-phosphate
-
Saccharomyces cerevisiae sedoheptulose 7-phosphate + ?
-
?
2.2.1.1 L-arabinose + ?
-
Spinacia oleracea ?
-
?
2.2.1.1 L-lyxose + ?
-
Spinacia oleracea ?
-
?

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.2.1.1 7 7.5 in phosphate buffer Escherichia coli
2.2.1.1 7.5 7.6
-
Saccharomyces pastorianus
2.2.1.1 7.5 7.6
-
Spinacia oleracea
2.2.1.1 7.5 7.6
-
Saccharomyces cerevisiae
2.2.1.1 7.7
-
-
Cyberlindnera jadinii
2.2.1.1 7.7
-
-
Homo sapiens
2.2.1.1 8 8.5
-
Homo sapiens
2.2.1.1 8 8.5 in glycylglycine buffer Escherichia coli