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Literature summary extracted from

  • Ingrosso, D.; Fowler, A.V.; Bleibaum, J.; Clarke, S.
    Sequence of the D-aspartyl/L-isoaspartyl protein methyltransferase from human erythrocytes. Common sequence motifs for protein, DNA, RNA, and small molecule S-adenosylmethionine-dependent methyltransferases (1989), J. Biol. Chem., 264, 20131-20139.
    View publication on PubMed

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.1.1.77 cytosol
-
Escherichia coli 5829
-
2.1.1.77 cytosol
-
Homo sapiens 5829
-
2.1.1.77 cytosol
-
Rattus norvegicus 5829
-

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.1.1.77 24580
-
amino acid sequence Homo sapiens
2.1.1.77 25000
-
-
Rattus norvegicus
2.1.1.77 25000
-
gel filtration Homo sapiens
2.1.1.77 26500
-
SDS-PAGE Homo sapiens
2.1.1.77 26500
-
SDS-PAGE Bos taurus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.1.1.77 S-adenosyl-L-methionine + protein L-isoaspartate Salmonella enterica subsp. enterica serovar Typhimurium
-
S-adenosyl-L-homocysteine + protein L-isoaspartate alpha-methyl ester
-
?
2.1.1.77 S-adenosyl-L-methionine + protein L-isoaspartate Escherichia coli
-
S-adenosyl-L-homocysteine + protein L-isoaspartate alpha-methyl ester
-
?
2.1.1.77 S-adenosyl-L-methionine + protein L-isoaspartate Homo sapiens
-
S-adenosyl-L-homocysteine + protein L-isoaspartate alpha-methyl ester
-
?
2.1.1.77 S-adenosyl-L-methionine + protein L-isoaspartate Rattus norvegicus
-
S-adenosyl-L-homocysteine + protein L-isoaspartate alpha-methyl ester
-
?
2.1.1.77 S-adenosyl-L-methionine + protein L-isoaspartate Bos taurus
-
S-adenosyl-L-homocysteine + protein L-isoaspartate alpha-methyl ester
-
?

Organism

EC Number Organism UniProt Comment Textmining
2.1.1.77 Bos taurus
-
bovine
-
2.1.1.77 Escherichia coli
-
-
-
2.1.1.77 Homo sapiens
-
human
-
2.1.1.77 Rattus norvegicus
-
-
-
2.1.1.77 Salmonella enterica subsp. enterica serovar Typhimurium
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.1.1.77
-
Homo sapiens

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.1.1.77 brain
-
Homo sapiens
-
2.1.1.77 brain
-
Rattus norvegicus
-
2.1.1.77 brain
-
Bos taurus
-
2.1.1.77 erythrocyte
-
Homo sapiens
-
2.1.1.77 erythrocyte
-
Rattus norvegicus
-
2.1.1.77 erythrocyte
-
Bos taurus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.1.1.77 S-adenosyl-L-methionine + protein L-isoaspartate
-
Salmonella enterica subsp. enterica serovar Typhimurium S-adenosyl-L-homocysteine + protein L-isoaspartate alpha-methyl ester
-
?
2.1.1.77 S-adenosyl-L-methionine + protein L-isoaspartate
-
Escherichia coli S-adenosyl-L-homocysteine + protein L-isoaspartate alpha-methyl ester
-
?
2.1.1.77 S-adenosyl-L-methionine + protein L-isoaspartate
-
Homo sapiens S-adenosyl-L-homocysteine + protein L-isoaspartate alpha-methyl ester
-
?
2.1.1.77 S-adenosyl-L-methionine + protein L-isoaspartate
-
Rattus norvegicus S-adenosyl-L-homocysteine + protein L-isoaspartate alpha-methyl ester
-
?
2.1.1.77 S-adenosyl-L-methionine + protein L-isoaspartate
-
Bos taurus S-adenosyl-L-homocysteine + protein L-isoaspartate alpha-methyl ester
-
?

Subunits

EC Number Subunits Comment Organism
2.1.1.77 monomer
-
Escherichia coli
2.1.1.77 monomer
-
Bos taurus
2.1.1.77 monomer 1 * 26500, SDS-PAGE Homo sapiens