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Literature summary extracted from

  • Gilbert, J.M.; Fowler, A.; Bleibaum, J.; Clarke, S.
    Purification of homologous protein carboxyl methyltransferase isozymes from human and bovine erythrocytes (1988), Biochemistry, 27, 5227-5233.
    View publication on PubMed

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.1.1.77 26500
-
 SDS-PAGE Homo sapiens
2.1.1.77 26500
-
 SDS-PAGE Bos taurus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.1.1.77 S-adenosyl-L-methionine + protein L-isoaspartate Salmonella enterica subsp. enterica serovar Typhimurium
-
 S-adenosyl-L-homocysteine + protein L-isoaspartate alpha-methyl ester
-
 ?
2.1.1.77 S-adenosyl-L-methionine + protein L-isoaspartate Escherichia coli
-
 S-adenosyl-L-homocysteine + protein L-isoaspartate alpha-methyl ester
-
 ?
2.1.1.77 S-adenosyl-L-methionine + protein L-isoaspartate Homo sapiens
-
 S-adenosyl-L-homocysteine + protein L-isoaspartate alpha-methyl ester
-
 ?
2.1.1.77 S-adenosyl-L-methionine + protein L-isoaspartate Bos taurus
-
 S-adenosyl-L-homocysteine + protein L-isoaspartate alpha-methyl ester
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.1.1.77 Bos taurus
-
 bovine
-
2.1.1.77 Escherichia coli
-
-
-
2.1.1.77 Homo sapiens
-
 human
-
2.1.1.77 Salmonella enterica subsp. enterica serovar Typhimurium
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.1.1.77 2 isozymes Homo sapiens
2.1.1.77 2 isozymes Bos taurus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.1.1.77 blood
-
 Homo sapiens
-
2.1.1.77 brain
-
 Homo sapiens
-
2.1.1.77 brain
-
 Bos taurus
-
2.1.1.77 erythrocyte
-
 Homo sapiens
-
2.1.1.77 erythrocyte
-
 Bos taurus
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
2.1.1.77 0.00427
-
-
 Homo sapiens

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.1.1.77 S-adenosyl-L-methionine + protein L-isoaspartate
-
 Salmonella enterica subsp. enterica serovar Typhimurium S-adenosyl-L-homocysteine + protein L-isoaspartate alpha-methyl ester
-
 ?
2.1.1.77 S-adenosyl-L-methionine + protein L-isoaspartate
-
 Escherichia coli S-adenosyl-L-homocysteine + protein L-isoaspartate alpha-methyl ester
-
 ?
2.1.1.77 S-adenosyl-L-methionine + protein L-isoaspartate
-
 Homo sapiens S-adenosyl-L-homocysteine + protein L-isoaspartate alpha-methyl ester
-
 ?
2.1.1.77 S-adenosyl-L-methionine + protein L-isoaspartate
-
 Bos taurus S-adenosyl-L-homocysteine + protein L-isoaspartate alpha-methyl ester
-
 ?

Subunits

EC Number Subunits Comment Organism
2.1.1.77 monomer
-
 Escherichia coli
2.1.1.77 monomer 1 * 26500, isoenzyme I and II, SDS-PAGE Homo sapiens
2.1.1.77 monomer 1 * 26500, isoenzyme I and II, SDS-PAGE Bos taurus