BRENDA - Enzyme Database show

The enzymatic synthesis of N-methylglutamic acid

Shaw, W.V.; Tsai, L.; Stadtman, E.R.; J. Biol. Chem. 241, 935-945 (1966)

Data extracted from this reference:

Inhibitors
EC Number
Inhibitors
Commentary
Organism
Structure
2.1.1.21
ammonia
competitive with respect to methylamine
Pseudomonas sp.
2.1.1.21
arsenite
-
Pseudomonas sp.
2.1.1.21
hydroxylamine
reversible
Pseudomonas sp.
2.1.1.21
iodoacetate
-
Pseudomonas sp.
2.1.1.21
N-ethylmaleimide
-
Pseudomonas sp.
2.1.1.21
p-chloromercuribenzoate
-
Pseudomonas sp.
Natural Substrates/ Products (Substrates)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
2.1.1.21
methylamine + L-glutamate
Pseudomonas sp.
involved in one carbon metabolism
NH3 + N-methyl-L-glutamate
-
Pseudomonas sp.
r
2.1.1.21
methylamine + L-glutamate
Pseudomonas sp. AM1(2006)
involved in one carbon metabolism
NH3 + N-methyl-L-glutamate
-
Pseudomonas sp. AM1(2006)
r
Organism
EC Number
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
2.1.1.21
Pseudomonas sp.
-
no activity when grown without methylamine in growth medium
-
2.1.1.21
Pseudomonas sp. AM1(2006)
-
no activity when grown without methylamine in growth medium
-
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
2.1.1.21
methylamine + L-glutamate
-
485233
Pseudomonas sp.
NH3 + N-methyl-L-glutamate
-
485233
Pseudomonas sp.
r
2.1.1.21
methylamine + L-glutamate
involved in one carbon metabolism
485233
Pseudomonas sp.
NH3 + N-methyl-L-glutamate
-
485233
Pseudomonas sp.
r
2.1.1.21
methylamine + L-glutamate
-
485233
Pseudomonas sp. AM1(2006)
NH3 + N-methyl-L-glutamate
-
485233
Pseudomonas sp. AM1(2006)
r
2.1.1.21
methylamine + L-glutamate
involved in one carbon metabolism
485233
Pseudomonas sp. AM1(2006)
NH3 + N-methyl-L-glutamate
-
485233
Pseudomonas sp. AM1(2006)
r
2.1.1.21
methylamine + L-glutamate-gamma-methylester
-
485233
Pseudomonas sp.
NH3 + N-methyl-L-glutamate-gamma-methyl ester
-
-
-
r
2.1.1.21
methylamine + L-glutamate-gamma-methylester
-
485233
Pseudomonas sp. AM1(2006)
NH3 + N-methyl-L-glutamate-gamma-methyl ester
-
-
-
r
2.1.1.21
methylamine + L-glutamine
-
485233
Pseudomonas sp.
?
-
-
-
r
2.1.1.21
methylamine + L-glutamine
-
485233
Pseudomonas sp. AM1(2006)
?
-
-
-
r
pH Optimum
EC Number
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
2.1.1.21
8.3
-
-
Pseudomonas sp.
pH Range
EC Number
pH Minimum
pH Maximum
Commentary
Organism
2.1.1.21
7
9
-
Pseudomonas sp.
Ki Value [mM]
EC Number
Ki Value [mM]
Ki Value maximum [mM]
Inhibitor
Commentary
Organism
Structure
2.1.1.21
49
-
ammonia
-
Pseudomonas sp.
Inhibitors (protein specific)
EC Number
Inhibitors
Commentary
Organism
Structure
2.1.1.21
ammonia
competitive with respect to methylamine
Pseudomonas sp.
2.1.1.21
arsenite
-
Pseudomonas sp.
2.1.1.21
hydroxylamine
reversible
Pseudomonas sp.
2.1.1.21
iodoacetate
-
Pseudomonas sp.
2.1.1.21
N-ethylmaleimide
-
Pseudomonas sp.
2.1.1.21
p-chloromercuribenzoate
-
Pseudomonas sp.
Ki Value [mM] (protein specific)
EC Number
Ki Value [mM]
Ki Value maximum [mM]
Inhibitor
Commentary
Organism
Structure
2.1.1.21
49
-
ammonia
-
Pseudomonas sp.
Natural Substrates/ Products (Substrates) (protein specific)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
2.1.1.21
methylamine + L-glutamate
Pseudomonas sp.
involved in one carbon metabolism
NH3 + N-methyl-L-glutamate
-
Pseudomonas sp.
r
2.1.1.21
methylamine + L-glutamate
Pseudomonas sp. AM1(2006)
involved in one carbon metabolism
NH3 + N-methyl-L-glutamate
-
Pseudomonas sp. AM1(2006)
r
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
2.1.1.21
methylamine + L-glutamate
-
485233
Pseudomonas sp.
NH3 + N-methyl-L-glutamate
-
485233
Pseudomonas sp.
r
2.1.1.21
methylamine + L-glutamate
involved in one carbon metabolism
485233
Pseudomonas sp.
NH3 + N-methyl-L-glutamate
-
485233
Pseudomonas sp.
r
2.1.1.21
methylamine + L-glutamate
-
485233
Pseudomonas sp. AM1(2006)
NH3 + N-methyl-L-glutamate
-
485233
Pseudomonas sp. AM1(2006)
r
2.1.1.21
methylamine + L-glutamate
involved in one carbon metabolism
485233
Pseudomonas sp. AM1(2006)
NH3 + N-methyl-L-glutamate
-
485233
Pseudomonas sp. AM1(2006)
r
2.1.1.21
methylamine + L-glutamate-gamma-methylester
-
485233
Pseudomonas sp.
NH3 + N-methyl-L-glutamate-gamma-methyl ester
-
-
-
r
2.1.1.21
methylamine + L-glutamate-gamma-methylester
-
485233
Pseudomonas sp. AM1(2006)
NH3 + N-methyl-L-glutamate-gamma-methyl ester
-
-
-
r
2.1.1.21
methylamine + L-glutamine
-
485233
Pseudomonas sp.
?
-
-
-
r
2.1.1.21
methylamine + L-glutamine
-
485233
Pseudomonas sp. AM1(2006)
?
-
-
-
r
pH Optimum (protein specific)
EC Number
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
2.1.1.21
8.3
-
-
Pseudomonas sp.
pH Range (protein specific)
EC Number
pH Minimum
pH Maximum
Commentary
Organism
2.1.1.21
7
9
-
Pseudomonas sp.