BRENDA - Enzyme Database

Overexpression of phosphatidylethanolamine N-methyltransferase 2 in CHO-K1 cells does not attenuate the activity of the CDP-choline pathway for phosphatidylcholine biosynthesis

Lee, M.W.; Bakovic, M.; Vance, D.E.; Biochem. J. 320, 905-910 (1996)
No PubMed abstract available

Data extracted from this reference:

Natural Substrates/ Products (Substrates)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
2.1.1.17
S-adenosyl-L-methionine + phosphatidylethanolamine
Cricetulus griseus
expression of PEMT2 in CHO cells does not down-regulate, but rather enhance, the expression of CTP-phosphocholine cytidylyltransferase
S-adenosyl-L-homocysteine + phosphatidyl-N-methylethanolamine
-
-
?
Organism
EC Number
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
2.1.1.17
Cricetulus griseus
-
-
-
Source Tissue
EC Number
Source Tissue
Commentary
Organism
Textmining
2.1.1.17
ovary cell line
cells express only a trace amount of phosphatidylethanolamine N-methyltransferase. Transfection of CHO cells, ovary cell line MT58, with PEMT2 cDNA behind the cytomegalovirus promoter result in a series of cell lines that overexpress PEMT2
Cricetulus griseus
-
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
2.1.1.17
S-adenosyl-L-methionine + phosphatidylethanolamine
-
485187
Cricetulus griseus
S-adenosyl-L-homocysteine + phosphatidyl-N-methylethanolamine
-
-
-
?
2.1.1.17
S-adenosyl-L-methionine + phosphatidylethanolamine
expression of PEMT2 in CHO cells does not down-regulate, but rather enhance, the expression of CTP-phosphocholine cytidylyltransferase
485187
Cricetulus griseus
S-adenosyl-L-homocysteine + phosphatidyl-N-methylethanolamine
-
-
-
?
Natural Substrates/ Products (Substrates) (protein specific)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
2.1.1.17
S-adenosyl-L-methionine + phosphatidylethanolamine
Cricetulus griseus
expression of PEMT2 in CHO cells does not down-regulate, but rather enhance, the expression of CTP-phosphocholine cytidylyltransferase
S-adenosyl-L-homocysteine + phosphatidyl-N-methylethanolamine
-
-
?
Source Tissue (protein specific)
EC Number
Source Tissue
Commentary
Organism
Textmining
2.1.1.17
ovary cell line
cells express only a trace amount of phosphatidylethanolamine N-methyltransferase. Transfection of CHO cells, ovary cell line MT58, with PEMT2 cDNA behind the cytomegalovirus promoter result in a series of cell lines that overexpress PEMT2
Cricetulus griseus
-
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
2.1.1.17
S-adenosyl-L-methionine + phosphatidylethanolamine
-
485187
Cricetulus griseus
S-adenosyl-L-homocysteine + phosphatidyl-N-methylethanolamine
-
-
-
?
2.1.1.17
S-adenosyl-L-methionine + phosphatidylethanolamine
expression of PEMT2 in CHO cells does not down-regulate, but rather enhance, the expression of CTP-phosphocholine cytidylyltransferase
485187
Cricetulus griseus
S-adenosyl-L-homocysteine + phosphatidyl-N-methylethanolamine
-
-
-
?