BRENDA - Enzyme Database

The role of phosphatidylethanolamine methylation in the secretion of very low density lipoproteins by cultured rat hepatocytes: rapid inhibition of phosphatidylethanolamine methylation by bezafibrate increases the density of apolipoprotein B48-containing lipoproteins

Nishimaki-Mogami, T.; Suzuki, K.; Takahashi, A.; Biochim. Biophys. Acta 1304, 21-31 (1996)

Data extracted from this reference:

Inhibitors
EC Number
Inhibitors
Commentary
Organism
Structure
2.1.1.17
bezafibrate
potent inhibitor of methylation of phosphoethanolamine
Rattus norvegicus
2.1.1.17
Clofibric acid
potent inhibitor of methylation of phosphoethanolamine
Rattus norvegicus
Natural Substrates/ Products (Substrates)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
2.1.1.17
S-adenosyl-L-methionine + phosphatidylethanolamine
Rattus norvegicus
methylation of phosphatidylethanolamine may play a role in very low density lipoprotein secretion
S-adenosyl-L-homocysteine + phosphatidyl-N-methylethanolamine
-
-
?
Organism
EC Number
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
2.1.1.17
Rattus norvegicus
-
-
-
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
2.1.1.17
S-adenosyl-L-methionine + phosphatidylethanolamine
-
485181
Rattus norvegicus
S-adenosyl-L-homocysteine + phosphatidyl-N-methylethanolamine
-
-
-
?
2.1.1.17
S-adenosyl-L-methionine + phosphatidylethanolamine
methylation of phosphatidylethanolamine may play a role in very low density lipoprotein secretion
485181
Rattus norvegicus
S-adenosyl-L-homocysteine + phosphatidyl-N-methylethanolamine
-
-
-
?
Inhibitors (protein specific)
EC Number
Inhibitors
Commentary
Organism
Structure
2.1.1.17
bezafibrate
potent inhibitor of methylation of phosphoethanolamine
Rattus norvegicus
2.1.1.17
Clofibric acid
potent inhibitor of methylation of phosphoethanolamine
Rattus norvegicus
Natural Substrates/ Products (Substrates) (protein specific)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
2.1.1.17
S-adenosyl-L-methionine + phosphatidylethanolamine
Rattus norvegicus
methylation of phosphatidylethanolamine may play a role in very low density lipoprotein secretion
S-adenosyl-L-homocysteine + phosphatidyl-N-methylethanolamine
-
-
?
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
2.1.1.17
S-adenosyl-L-methionine + phosphatidylethanolamine
-
485181
Rattus norvegicus
S-adenosyl-L-homocysteine + phosphatidyl-N-methylethanolamine
-
-
-
?
2.1.1.17
S-adenosyl-L-methionine + phosphatidylethanolamine
methylation of phosphatidylethanolamine may play a role in very low density lipoprotein secretion
485181
Rattus norvegicus
S-adenosyl-L-homocysteine + phosphatidyl-N-methylethanolamine
-
-
-
?