EC Number | Activating Compound | Comment | Organism | Structure |
---|---|---|---|---|
2.1.1.137 | dithiothreitol | weak activation | Cricetinae | |
2.1.1.137 | glutathione | a 4fold increase in glutathione concentration, 2 to 8 mM, leads to a 2fold increase in enzyme activity, reducing environment is required for enzyme activity | Cricetinae | |
2.1.1.137 | L-cysteine | activates stronger than glutathione | Cricetinae |
EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
2.1.1.137 | 0.002 | - |
arsenite | - |
Cricetinae |
EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|---|
2.1.1.137 | cytosol | - |
Cricetinae | 5829 | - |
EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|---|
2.1.1.137 | 46000 | - |
gel filtration | Cricetinae |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.1.1.137 | S-adenosyl-L-methionine + arsenite | Cricetinae | - |
S-adenosyl-L-homocysteine + methylarsonate | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.1.1.137 | Cricetinae | - |
male golden syrian hamster | - |
EC Number | Purification (Comment) | Organism |
---|---|---|
2.1.1.137 | DEAE anion exchange chromatography, Sephadex G-200, High Q anion exchange chromatographie, 40fold purification | Cricetinae |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
2.1.1.137 | liver | - |
Cricetinae | - |
EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|---|
2.1.1.137 | 0.0000000283 | - |
- |
Cricetinae |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.1.1.137 | S-adenosyl-L-methionine + arsenite | - |
Cricetinae | S-adenosyl-L-homocysteine + methylarsonate | - |
? |
EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|---|
2.1.1.137 | 7.6 | - |
- |
Cricetinae |
EC Number | Cofactor | Comment | Organism | Structure |
---|---|---|---|---|
2.1.1.137 | S-adenosyl-L-methionine | - |
Cricetinae |