BRENDA - Enzyme Database

On the mechanism of the mitochondrial decarboxylation of phosphatidylserine

Hovius, R.; Faber, B.; Brigot, B.; Nicolay, K.; de Kruijff, B.; J. Biol. Chem. 267, 16790-16795 (1992)

Data extracted from this reference:

Inhibitors
EC Number
Inhibitors
Commentary
Organism
Structure
4.1.1.65
nitrophene
-
Rattus norvegicus
Localization
EC Number
Localization
Commentary
Organism
GeneOntology No.
Textmining
4.1.1.65
membrane
exclusively in the inner mitochondrial membrane; phosphatidylserine flows from the outer membrane to the inner membrane through contact sites between inner and outer membrane to become decarboxylated and the formed phosphatidylethanolamine flows directly back to the outer membrane, without mixing with inner membrane phosphatidylamine
Rattus norvegicus
16020
-
4.1.1.65
mitochondrial inner membrane
exclusively in the inner mitochondrial membrane
Rattus norvegicus
5743
-
Organism
EC Number
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
4.1.1.65
Rattus norvegicus
-
-
-
Source Tissue
EC Number
Source Tissue
Commentary
Organism
Textmining
4.1.1.65
liver
-
Rattus norvegicus
-
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
4.1.1.65
Phosphatidyl-L-serine
-
4791
Rattus norvegicus
Phosphatidylethanolamine + CO2
-
4791
Rattus norvegicus
-
Inhibitors (protein specific)
EC Number
Inhibitors
Commentary
Organism
Structure
4.1.1.65
nitrophene
-
Rattus norvegicus
Localization (protein specific)
EC Number
Localization
Commentary
Organism
GeneOntology No.
Textmining
4.1.1.65
membrane
exclusively in the inner mitochondrial membrane; phosphatidylserine flows from the outer membrane to the inner membrane through contact sites between inner and outer membrane to become decarboxylated and the formed phosphatidylethanolamine flows directly back to the outer membrane, without mixing with inner membrane phosphatidylamine
Rattus norvegicus
16020
-
4.1.1.65
mitochondrial inner membrane
exclusively in the inner mitochondrial membrane
Rattus norvegicus
5743
-
Source Tissue (protein specific)
EC Number
Source Tissue
Commentary
Organism
Textmining
4.1.1.65
liver
-
Rattus norvegicus
-
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
4.1.1.65
Phosphatidyl-L-serine
-
4791
Rattus norvegicus
Phosphatidylethanolamine + CO2
-
4791
Rattus norvegicus
-