BRENDA - Enzyme Database

Characterization of brain phosphatidylserine decarboxylase: localization in the mitochondrial inner membrane

Percy, A.K.; Moore, J.F.; Carson, M.A.; Waechter, C.J.; Arch. Biochem. Biophys. 223, 484-494 (1983)

Data extracted from this reference:

Activating Compound
EC Number
Activating Compound
Commentary
Organism
Structure
4.1.1.65
Cutsum
maximal activity in presence of 0.1% cutsum
Bos taurus
4.1.1.65
sodium taurocholate
maximal activity in presence of 0.1% sodium taurocholate
Bos taurus
Inhibitors
EC Number
Inhibitors
Commentary
Organism
Structure
4.1.1.65
hydroxylamine
-
Bos taurus
4.1.1.65
hydroxylamine
-
Rattus norvegicus
4.1.1.65
p-hydroxymercuribenzoate
-
Bos taurus
KM Value [mM]
EC Number
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Organism
Structure
4.1.1.65
2.4
-
phosphatidylserine
-
Bos taurus
Localization
EC Number
Localization
Commentary
Organism
GeneOntology No.
Textmining
4.1.1.65
membrane
-
Rattus norvegicus
16020
-
4.1.1.65
mitochondrial inner membrane
inner membrane
Bos taurus
5743
-
4.1.1.65
mitochondrial inner membrane
membrane
Rattus norvegicus
5743
-
Metals/Ions
EC Number
Metals/Ions
Commentary
Organism
Structure
4.1.1.65
additional information
no requirement for divalent metal ions
Bos taurus
Organism
EC Number
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
4.1.1.65
Bos taurus
-
calf
-
4.1.1.65
Rattus norvegicus
-
-
-
Source Tissue
EC Number
Source Tissue
Commentary
Organism
Textmining
4.1.1.65
brain
-
Bos taurus
-
4.1.1.65
brain
-
Rattus norvegicus
-
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
4.1.1.65
Phosphatidyl-L-serine
-
4776
Rattus norvegicus
Phosphatidylethanolamine + CO2
-
4776
Rattus norvegicus
-
4.1.1.65
Phosphatidyl-L-serine
-
4776
Bos taurus
Phosphatidylethanolamine + CO2
-
4776
Bos taurus
-
Temperature Optimum [°C]
EC Number
Temperature Optimum [°C]
Temperature Optimum Maximum [°C]
Commentary
Organism
4.1.1.65
37
40
-
Bos taurus
Temperature Range [°C]
EC Number
Temperature Minimum [°C]
Temperature Maximum [°C]
Commentary
Organism
4.1.1.65
35
50
35°C: about 60% of maximal activity, 50°C: about 25% of maximal activity
Bos taurus
pH Optimum
EC Number
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
4.1.1.65
7
-
-
Bos taurus
pH Range
EC Number
pH Minimum
pH Maximum
Commentary
Organism
4.1.1.65
6
8.5
pH 6.0: about 35% of maximal activity, pH 8.5: about 50% of maximal activity
Bos taurus
Activating Compound (protein specific)
EC Number
Activating Compound
Commentary
Organism
Structure
4.1.1.65
Cutsum
maximal activity in presence of 0.1% cutsum
Bos taurus
4.1.1.65
sodium taurocholate
maximal activity in presence of 0.1% sodium taurocholate
Bos taurus
Inhibitors (protein specific)
EC Number
Inhibitors
Commentary
Organism
Structure
4.1.1.65
hydroxylamine
-
Bos taurus
4.1.1.65
hydroxylamine
-
Rattus norvegicus
4.1.1.65
p-hydroxymercuribenzoate
-
Bos taurus
KM Value [mM] (protein specific)
EC Number
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Organism
Structure
4.1.1.65
2.4
-
phosphatidylserine
-
Bos taurus
Localization (protein specific)
EC Number
Localization
Commentary
Organism
GeneOntology No.
Textmining
4.1.1.65
membrane
-
Rattus norvegicus
16020
-
4.1.1.65
mitochondrial inner membrane
inner membrane
Bos taurus
5743
-
4.1.1.65
mitochondrial inner membrane
membrane
Rattus norvegicus
5743
-
Metals/Ions (protein specific)
EC Number
Metals/Ions
Commentary
Organism
Structure
4.1.1.65
additional information
no requirement for divalent metal ions
Bos taurus
Source Tissue (protein specific)
EC Number
Source Tissue
Commentary
Organism
Textmining
4.1.1.65
brain
-
Bos taurus
-
4.1.1.65
brain
-
Rattus norvegicus
-
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
4.1.1.65
Phosphatidyl-L-serine
-
4776
Rattus norvegicus
Phosphatidylethanolamine + CO2
-
4776
Rattus norvegicus
-
4.1.1.65
Phosphatidyl-L-serine
-
4776
Bos taurus
Phosphatidylethanolamine + CO2
-
4776
Bos taurus
-
Temperature Optimum [°C] (protein specific)
EC Number
Temperature Optimum [°C]
Temperature Optimum Maximum [°C]
Commentary
Organism
4.1.1.65
37
40
-
Bos taurus
Temperature Range [°C] (protein specific)
EC Number
Temperature Minimum [°C]
Temperature Maximum [°C]
Commentary
Organism
4.1.1.65
35
50
35°C: about 60% of maximal activity, 50°C: about 25% of maximal activity
Bos taurus
pH Optimum (protein specific)
EC Number
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
4.1.1.65
7
-
-
Bos taurus
pH Range (protein specific)
EC Number
pH Minimum
pH Maximum
Commentary
Organism
4.1.1.65
6
8.5
pH 6.0: about 35% of maximal activity, pH 8.5: about 50% of maximal activity
Bos taurus