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Literature summary extracted from

  • Dowhan, W.; Wickner, W.T.; Kennedy, E.P.
    Purification and properties of phosphatidylserine decarboxylase from Escherichia coli (1974), J. Biol. Chem., 249, 3079-3084.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
4.1.1.65 nonionic detergents e.g. Triton X-100, absolute requirement Escherichia coli

Inhibitors

EC Number Inhibitors Comment Organism Structure
4.1.1.65 ionic detergents e.g., Barlox-12, SDS Escherichia coli

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
4.1.1.65 membrane bound to Escherichia coli 16020
-

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
4.1.1.65 36500
-
 x * 36500, SDS-PAGE Escherichia coli
4.1.1.65 60000 170000 sucrose density gradient centrifugation, in presence of Triton Escherichia coli
4.1.1.65 170000
-
 sucrose density gradient centrifugation in absence of Triton Escherichia coli
4.1.1.65 400000
-
 gel filtration Escherichia coli

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
4.1.1.65 phosphatidyl-L-serine Escherichia coli the enzyme catalyzes the final step in the biosynthesis of phosphatidylethanolamine ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
4.1.1.65 Escherichia coli
-
-
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
4.1.1.65 49
-
-
 Escherichia coli

Storage Stability

EC Number Storage Stability Organism
4.1.1.65 -25°C, pH 6.0-7.8, 10% glycerol, 0.1% Triton X-100, stable for 1.5 years. 0°C, stable for several months. Room temperature, stable for at least 1 week Escherichia coli

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.1.1.65 Phosphatidyl-L-serine
-
 Escherichia coli Phosphatidylethanolamine + CO2
-
 ?
4.1.1.65 phosphatidyl-L-serine the enzyme catalyzes the final step in the biosynthesis of phosphatidylethanolamine Escherichia coli ?
-
 ?

Subunits

EC Number Subunits Comment Organism
4.1.1.65 ? x * 36500, SDS-PAGE Escherichia coli
4.1.1.65 dimer
-
 Escherichia coli

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
4.1.1.65 6.5 7.5
-
 Escherichia coli