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Literature summary extracted from

  • Lazard, M.; Mirande, M.; Waller, J.P.
    Purification and characterization of the isoleucyl-tRNA synthetase component from the high molecular weight complex of sheep liver. A hydrophobic metalloprotein (1985), Biochemistry, 24, 5099-5106.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
6.1.1.5 1,10-phenanthroline
-
 Ovis aries
6.1.1.5 2,2'-bipyridyl
-
 Ovis aries

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
6.1.1.5 Zinc contains 1 Zn2+ per polypeptide chain Ovis aries

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
6.1.1.5 139000
-
 x * 139000, SDS-PAGE Ovis aries
6.1.1.5 200000
-
 gel filtration Ovis aries

Organism

EC Number Organism UniProt Comment Textmining
6.1.1.5 Ovis aries
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
6.1.1.5
-
 Ovis aries

Source Tissue

EC Number Source Tissue Comment Organism Textmining
6.1.1.5 liver
-
 Ovis aries
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
6.1.1.5 0.06
-
-
 Ovis aries

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
6.1.1.5 ATP + L-isoleucine + tRNAIle
-
 Ovis aries AMP + diphosphate + L-isoleucyl-tRNAIle
-
 ?

Subunits

EC Number Subunits Comment Organism
6.1.1.5 ? x * 139000, SDS-PAGE Ovis aries