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Literature summary extracted from

  • Stevenson, D.E.; Akhtar, M.; Gani, D.
    Streptomyces L-methionine decarboxylase: purification and properties of the enzyme and stereochemical course of substrate decarboxylation (1990), Biochemistry, 29, 7660-7666.
    View publication on PubMed

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
4.1.1.57 59000
-
 2 * 59000, SDS-PAGE Streptomyces sp.
4.1.1.57 100000
-
 gel filtration Streptomyces sp.

Organism

EC Number Organism UniProt Comment Textmining
4.1.1.57 Streptomyces sp.
-
 ATCC 21020
-

Purification (Commentary)

EC Number Purification (Comment) Organism
4.1.1.57
-
 Streptomyces sp.

Reaction

EC Number Reaction Comment Organism Reaction ID
4.1.1.57 L-methionine = 3-(methylsulfanyl)propanamine + CO2 reaction with retention of configuration at Calpha Streptomyces sp.
a

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
4.1.1.57 28
-
-
 Streptomyces sp.

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.1.1.57 L-Ethionine
-
 Streptomyces sp. 3-Ethylthiopropanamine + CO2
-
 ?
4.1.1.57 L-Ile
-
 Streptomyces sp. 2-Methylbutylamine + CO2
-
 ?
4.1.1.57 L-Leu
-
 Streptomyces sp. 3-Methylbutylamine + CO2
-
 ?
4.1.1.57 L-Met
-
 Streptomyces sp. 3-Methylthiopropanamine + CO2
-
 ?
4.1.1.57 L-norleucine
-
 Streptomyces sp. pentanamine + CO2
-
 ?
4.1.1.57 L-Norvaline
-
 Streptomyces sp. Butylamine + CO2
-
 ?
4.1.1.57 S-Ethyl-L-Cys
-
 Streptomyces sp. 2-Ethylthioethanamine + CO2
-
 ?

Subunits

EC Number Subunits Comment Organism
4.1.1.57 dimer 2 * 59000, SDS-PAGE Streptomyces sp.

Turnover Number [1/s]

EC Number Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
4.1.1.57 120
-
 L-Met
-
 Streptomyces sp.

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
4.1.1.57 6.9
-
-
 Streptomyces sp.

Cofactor

EC Number Cofactor Comment Organism Structure
4.1.1.57 pyridoxal 5'-phosphate coenzyme Streptomyces sp.