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Literature summary extracted from

  • Persson, K.; Aslund, L.; Grahn, B.; Hanke, J.; Heby, O.
    Trypanosoma cruzi has not lost its S-adenosylmethionine decarboxylase: characterization of the gene and the encoded enzyme (1998), Biochem. J., 333, 527-537.
    View publication on PubMedView publication on EuropePMC

Activating Compound

EC Number Activating Compound Comment Organism Structure
4.1.1.50 putrescine stimulation Trypanosoma cruzi

Cloned(Commentary)

EC Number Cloned (Comment) Organism
4.1.1.50 expression in Escherichia coli Trypanosoma cruzi

Inhibitors

EC Number Inhibitors Comment Organism Structure
4.1.1.50 methylglyoxal bis(guanylhydrazone) poor Trypanosoma cruzi
4.1.1.50 spermidine weak Trypanosoma cruzi
4.1.1.50 spermine strong Trypanosoma cruzi

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
4.1.1.50 0.21
-
 S-adenosyl-L-methionine
-
 Trypanosoma cruzi

Organism

EC Number Organism UniProt Comment Textmining
4.1.1.50 Trypanosoma cruzi
-
-
-

Posttranslational Modification

EC Number Posttranslational Modification Comment Organism
4.1.1.50 proteolytic modification the recombinant protein undergoes autocatalytic cleavage, generating a 33000-34000 Da alpha-subunit and a 9000 Da beta-subunit Trypanosoma cruzi

Purification (Commentary)

EC Number Purification (Comment) Organism
4.1.1.50 recombinant enzyme Trypanosoma cruzi

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.1.1.50 S-adenosyl-L-methionine
-
 Trypanosoma cruzi (5-deoxy-5-adenosyl)(3-aminopropyl)methylsulfonium salt + CO2
-
 ?