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Literature summary extracted from

  • Hulett, F.M.; DeMoss, J.A.
    Subunit structure of anthranilate synthetase from Neurospora crassa (1975), J. Biol. Chem., 250, 6648-6652.
    View publication on PubMed

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
4.1.1.48 70000
-
 2 * 94000 + 2 * 70000, anthranilate synthetase complex, one subunit is a trifunctional peptide which contains the catalytic sites for the phosphoribosylanthranilate isomerase and indoleglycerol phosphate synthetase reactions, and associates with the second subunit to form glutamine-dependent anthranilate synthetase, SDS-PAGE Neurospora crassa
4.1.1.48 94000
-
 2 * 94000 + 2 * 70000, anthranilate synthetase complex, one subunit is a trifunctional peptide which contains the catalytic sites for the phosphoribosylanthranilate isomerase and indoleglycerol phosphate synthetase reactions, and associates with the second subunit to form glutamine-dependent anthranilate synthetase, SDS-PAGE Neurospora crassa
4.1.1.48 320000 340000 anthranilate synthetase complex, gel filtration Neurospora crassa
4.1.3.27 70000
-
 alpha2,beta2, 2 * 70000 + 2 * 94000, SDS-PAGE Neurospora crassa
4.1.3.27 94000
-
 alpha2,beta2, 2 * 70000 + 2 * 94000, SDS-PAGE Neurospora crassa

Organism

EC Number Organism UniProt Comment Textmining
4.1.1.48 Neurospora crassa
-
-
-
4.1.3.27 Neurospora crassa
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.1.1.48 1-(2-Carboxyphenylamino)-1-deoxy-D-ribulose-5-phosphate
-
 Neurospora crassa 1-(3-Indolyl)glycerol-3-phosphate + CO2 + H2O
-
 ?
4.1.3.27 chorismate + L-Gln
-
 Neurospora crassa anthranilate + pyruvate + L-glutamate
-
 ?

Subunits

EC Number Subunits Comment Organism
4.1.1.48 tetramer 2 * 94000 + 2 * 70000, anthranilate synthetase complex, one subunit is a trifunctional peptide which contains the catalytic sites for the phosphoribosylanthranilate isomerase and indoleglycerol phosphate synthetase reactions, and associates with the second subunit to form glutamine-dependent anthranilate synthetase, SDS-PAGE Neurospora crassa
4.1.3.27 More one subunit is a trifunctional peptide which contains the catalytic sites for phosphoribosylanthranilate isomerase and indoleglycerol phosphate synthetase reactions, and associates with the second subunit to form Gln-dependent anthranilate synthetase Neurospora crassa
4.1.3.27 tetramer alpha2,beta2, 2 * 70000 + 2 * 94000, SDS-PAGE Neurospora crassa