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Literature summary extracted from
- Enzyme-catalysed non-oxidative decarboxylation of aromatic acids. I. Piurification and spectroscopic properties of 2,3-dihydroxybenzoic acid decarboxylase from Aspergillus niger (1987), Biochem. Biophys. Res. Commun., 145, 586-595.
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 4.1.1.46 | 2,3-Dihydroxybenzaldehyde | - |
Aspergillus niger |  |
| 4.1.1.46 | 2,4-Dihydroxybenzoate | - |
Aspergillus niger | |
| 4.1.1.46 | 3,4-dihydroxybenzoate | weak | Aspergillus niger | |
| 4.1.1.46 | 3-Hydroxyanthranilate | - |
Aspergillus niger | |
| 4.1.1.46 | 3-hydroxybenzoate | weak | Aspergillus niger | |
| 4.1.1.46 | anthranilate | - |
Aspergillus niger | |
| 4.1.1.46 | benzoate | weak | Aspergillus niger | |
| 4.1.1.46 | additional information | no inhibition by 4-hydroxybenzoate | Aspergillus niger | |
| 4.1.1.46 | salicylate | - |
Aspergillus niger | |
KM Value [mM]
| EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|---|
| 4.1.1.46 | 0.34 | - |
2,3-Dihydroxybenzoate | - |
Aspergillus niger | |
Molecular Weight [Da]
| EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|---|
| 4.1.1.46 | 28000 | - |
4 * 28000, SDS-PAGE | Aspergillus niger |
| 4.1.1.46 | 120000 | - |
gel filtration | Aspergillus niger |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 4.1.1.46 | Aspergillus niger | - |
- |
- |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 4.1.1.46 | - |
Aspergillus niger |
Specific Activity [micromol/min/mg]
| EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|---|
| 4.1.1.46 | 15.9 | - |
- |
Aspergillus niger |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 4.1.1.46 | 2,3-Dihydroxybenzoate | - |
Aspergillus niger | Catechol + CO2 | - |
? | |
Subunits
| EC Number | Subunits | Comment | Organism |
|---|---|---|---|
| 4.1.1.46 | tetramer | 4 * 28000, SDS-PAGE | Aspergillus niger |
pH Optimum
| EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|---|
| 4.1.1.46 | 5.2 | - |
- |
Aspergillus niger |
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Release 2023.1 (January 2023)
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