EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
4.1.1.45 | diethyldicarbonate | - |
Sus scrofa | |
4.1.1.45 | iodoacetamide | - |
Sus scrofa | |
4.1.1.45 | Monoiodoacetic acid | - |
Sus scrofa | |
4.1.1.45 | N-Acetylimidazole | - |
Sus scrofa | |
4.1.1.45 | NEM | - |
Sus scrofa | |
4.1.1.45 | PCMB | - |
Sus scrofa |
EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
4.1.1.45 | 0.0161 | - |
2-amino-3-(3-oxoprop-1-en-1-yl)but-2-enedioate | - |
Sus scrofa |
EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|---|
4.1.1.45 | 41000 | - |
1 * 41000, SDS-PAGE | Sus scrofa |
4.1.1.45 | 58000 | - |
gel filtration | Sus scrofa |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
4.1.1.45 | 2-amino-3-(3-oxoprop-1-en-1-yl)but-2-enedioate | Sus scrofa | key enzyme of niacin synthesis from Trp | ? | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
4.1.1.45 | Sus scrofa | - |
hog | - |
EC Number | Purification (Comment) | Organism |
---|---|---|
4.1.1.45 | - |
Sus scrofa |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
4.1.1.45 | kidney | - |
Sus scrofa | - |
EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|---|
4.1.1.45 | 3.789 | - |
- |
Sus scrofa |
EC Number | Storage Stability | Organism |
---|---|---|
4.1.1.45 | -20°C, 50 mM potassium phosphate buffer, pH 7.0, 0.14 M KCl, 5 mM 2-mercaptoethanol, 1 mM dithiothreitol, 1 mM EDTA, 20% glycerol, stable for at least 1 month | Sus scrofa |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
4.1.1.45 | 2-amino-3-(3-oxoprop-1-en-1-yl)but-2-enedioate | - |
Sus scrofa | 2-aminomuconate semialdehyde + CO2 | - |
? | |
4.1.1.45 | 2-amino-3-(3-oxoprop-1-en-1-yl)but-2-enedioate | key enzyme of niacin synthesis from Trp | Sus scrofa | ? | - |
? |
EC Number | Subunits | Comment | Organism |
---|---|---|---|
4.1.1.45 | monomer | 1 * 41000, SDS-PAGE | Sus scrofa |
EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|---|
4.1.1.45 | 7.5 | - |
- |
Sus scrofa |
EC Number | pH Minimum | pH Maximum | Comment | Organism |
---|---|---|---|---|
4.1.1.45 | 6 | 9 | pH 6: about 40% of maximal activity, pH 9.0: about 35% of maximal activity | Sus scrofa |