Literature summary extracted from

Glasfeld, E.; Landro, J.A.; Schimmel, P.
C-terminal zinc-containing peptide required for RNA recognition by a class I tRNA synthetase (1996), Biochemistry, 35, 4139-4145.

KM Value [mM]

EC Number	KM Value [mM]	KM Value Maximum [mM]	Substrate	Comment	Organism	Structure
6.1.1.5	0.00028	-	ATP	-	Escherichia coli
6.1.1.5	0.0036	-	Ile	-	Escherichia coli

Metals/Ions

EC Number	Metals/Ions	Comment	Organism	Structure
6.1.1.5	Zinc	required	Escherichia coli
6.1.1.5	Zinc	bound to a Cys4 cluster at the C-terminal end of the polypeptide	Escherichia coli

Organism

EC Number	Organism	UniProt	Comment	Textmining
6.1.1.5	Escherichia coli	-	-	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
6.1.1.5	ATP + L-isoleucine + tRNAIle	-	Escherichia coli	AMP + diphosphate + L-isoleucyl-tRNAIle	-	?

Turnover Number [1/s]

EC Number	Turnover Number Minimum [1/s]	Turnover Number Maximum [1/s]	Substrate	Comment	Organism	Structure
6.1.1.5	80.4	-	ATP	wild-type enzyme	Escherichia coli

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Release 2023.1 (January 2023)