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Literature summary extracted from

  • Brohn, F.H.; Trager, W.
    Coenzyme A requirement of malaria parasites: enzymes of coenzyme A biosynthesis in normal duck erythrocytes and erythrocytes infected with Plasmodium lophurae (1975), Proc. Natl. Acad. Sci. USA, 72, 2456-2458.
    View publication on PubMedView publication on EuropePMC

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.7.1.24 cytosol
-
 Anas platyrhynchos 5829
-
2.7.7.3 cytosol
-
 Anas sp. 5829
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.7.7.3 ATP + pantetheine 4'-phosphate Anas sp.
-
 diphosphate + 3'-dephospho-CoA
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.7.1.24 Anas platyrhynchos
-
 duck
-
2.7.1.24 no activity in Plasmodium lophurae
-
-
-
2.7.7.3 Anas sp.
-
-
-
2.7.7.3 no activity in Plasmodium lophurae
-
 avian malaria parasite
-
4.1.1.36 Anas platyrhynchos
-
-
-
4.1.1.36 no activity in Plasmodium lophurae
-
-
-
6.3.2.5 Anas platyrhynchos
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.7.1.24 erythrocyte normal and Plasmodium lophurae-infected Anas platyrhynchos
-
2.7.7.3 erythrocyte normal and Plasmodium lophurae-infected Anas sp.
-
4.1.1.36 erythrocyte normal and infected with Plasmodium lophurae Anas platyrhynchos
-
6.3.2.5 erythrocyte normal and infected with Plasmodium lophurae Anas platyrhynchos
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
2.7.1.24 additional information
-
 specific activity per mg hemoglobin Anas platyrhynchos

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.1.24 ATP + dephospho-CoA
-
 Anas platyrhynchos ADP + CoA
-
 ?
2.7.7.3 ATP + pantetheine 4'-phosphate
-
 Anas sp. diphosphate + 3'-dephospho-CoA
-
 ?
4.1.1.36 N-((R)-4-Phosphopantothenoyl)-L-Cys
-
 Anas platyrhynchos Pantotheine 4-phosphate + CO2
-
 ?

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
2.7.1.24 41
-
 assay at Anas platyrhynchos
2.7.7.3 41
-
 assay at Anas sp.