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Literature summary extracted from

  • Aebi, H.E.
    Catalase. Hydrogen-peroxide:hydrogen-peroxide oxidoreductase E.C. 1.11.1.6 (1983), Methods Enzym. Anal. , 3rd Ed. (Bergmeyer, H. U. , ed. ), 3, 373-386.
No PubMed abstract available

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.11.1.6 3-amino-1H-1,2,4-triazole exclusive in vivo inhibitor Homo sapiens
1.11.1.6 acetic acid in vitro inhibitor Homo sapiens
1.11.1.6 ascorbate in vitro inhibitor Homo sapiens
1.11.1.6 BrCN acting in vitro Homo sapiens
1.11.1.6 ethanol in vitro inhibitor Homo sapiens
1.11.1.6 F- in vitro inhibitor Homo sapiens
1.11.1.6 formic acid in vitro inhibitor Homo sapiens
1.11.1.6 hydroxylamine in vitro inhibitor Homo sapiens
1.11.1.6 KCN acting in vitro Homo sapiens
1.11.1.6 methanol in vitro inhibitor Homo sapiens
1.11.1.6 NaN3 acting in vitro Homo sapiens
1.11.1.6 nitrite in vitro inhibitor Homo sapiens

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
1.11.1.6 cytoplasm erythrocytes Homo sapiens 5737
-
1.11.1.6 mitochondrion mainly in liver and kidney Homo sapiens 5739
-
1.11.1.6 peroxisome mainly in liver and kidney Homo sapiens 5777
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.11.1.6 H2O2 Homo sapiens abnormal reaction kinetics O2 + H2O
-
 ?
1.11.1.6 H2O2 Homo sapiens involved in acatalasemia O2 + H2O
-
 ?
1.11.1.6 H2O2 Homo sapiens regulator of H2O2-levels or protective function for hemoglobin or other SH-proteins O2 + H2O
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.11.1.6 Homo sapiens
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.11.1.6 erythrocyte
-
 Homo sapiens
-
1.11.1.6 kidney
-
 Homo sapiens
-
1.11.1.6 liver
-
 Homo sapiens
-

Storage Stability

EC Number Storage Stability Organism
1.11.1.6 2°C, intact erythrocytes or concentrated hemolysates, 6 days Homo sapiens

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.11.1.6 ethanol + H2O2
-
 Homo sapiens acetaldehyde + ?
-
 ?
1.11.1.6 formic acid + H2O2
-
 Homo sapiens ?
-
 ?
1.11.1.6 H2O2 abnormal reaction kinetics Homo sapiens O2 + H2O
-
 ?
1.11.1.6 H2O2 involved in acatalasemia Homo sapiens O2 + H2O
-
 ?
1.11.1.6 H2O2 regulator of H2O2-levels or protective function for hemoglobin or other SH-proteins Homo sapiens O2 + H2O
-
 ?
1.11.1.6 methanol + H2O2
-
 Homo sapiens formaldehyde + ?
-
 ?

Temperature Range [°C]

EC Number Temperature Minimum [°C] Temperature Maximum [°C] Comment Organism
1.11.1.6
-
 37
-
 Homo sapiens

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
1.11.1.6 6.8 7.5
-
 Homo sapiens

Cofactor

EC Number Cofactor Comment Organism Structure
1.11.1.6 heme
-
 Homo sapiens