Literature summary extracted from

Divi, R.L.; Doerge, D.R.
Inhibition of thyroid peroxidase by dietary flavonoids (1996), Chem. Res. Toxicol., 9, 16-23.

Inhibitors

EC Number	Inhibitors	Comment	Organism	Structure
1.11.1.8	fisetin	-	Sus scrofa
1.11.1.8	kaempferol	-	Sus scrofa
1.11.1.8	morin	-	Sus scrofa
1.11.1.8	myricetin	non competitive with I-	Sus scrofa
1.11.1.8	naringenin	non competitive with I-, competitive with H2O2	Sus scrofa
1.11.1.8	quercetin	-	Sus scrofa
1.11.1.8	rutin	-	Sus scrofa

KM Value [mM]

EC Number	KM Value [mM]	KM Value Maximum [mM]	Substrate	Comment	Organism	Structure
1.11.1.8	0.034	-	H2O2	-	Sus scrofa

Natural Substrates/ Products (Substrates)

EC Number	Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
1.11.1.8	iodide + H2O2	Sus scrofa	-	iodine + H2O	-	?

Organism

EC Number	Organism	UniProt	Comment	Textmining
1.11.1.8	Sus scrofa	-	pig, female	-

Purification (Commentary)

EC Number	Purification (Comment)	Organism
1.11.1.8	-	Sus scrofa

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
1.11.1.8	biochanin A + H2O2 + I-	-	Sus scrofa	6,8-diiodobiochanin A + H2O	-	?
1.11.1.8	guaiacol + H2O2 + I-	-	Sus scrofa	tetraguaiacol + H2O	-	?
1.11.1.8	iodide + H2O2	-	Sus scrofa	iodine + H2O	-	?

Ki Value [mM]

EC Number	Ki Value [mM]	Ki Value maximum [mM]	Inhibitor	Comment	Organism	Structure
1.11.1.8	0.001	-	myricetin	-	Sus scrofa
1.11.1.8	0.006	-	kaempferol	-	Sus scrofa
1.11.1.8	0.007	-	quercetin	-	Sus scrofa
1.11.1.8	0.007	-	naringenin	-	Sus scrofa
1.11.1.8	0.013	-	morin	-	Sus scrofa

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Release 2023.1 (January 2023)