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Literature summary extracted from

  • May, S.W.; Phillips, R.S.
    Protocatechuate 3,4-dioxygenase: implications of ionization effects on binding and dissociation of halohydroxybenzoates and on catalytic turnover (1979), Biochemistry, 18, 5933-5939.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.13.11.3 3,5-Dichloro-4-hydroxybenzoate
-
 Pseudomonas aeruginosa
1.13.11.3 3-Bromo-4-hydroxybenzoate
-
 Pseudomonas aeruginosa
1.13.11.3 3-Chloro-4-hydroxybenzoate
-
 Pseudomonas aeruginosa
1.13.11.3 3-Fluoro-4-hydroxybenzoate
-
 Pseudomonas aeruginosa
1.13.11.3 4-Fluoro-3-hydroxybenzoate
-
 Pseudomonas aeruginosa
1.13.11.3 4-hydroxybenzoate
-
 Pseudomonas aeruginosa

Organism

EC Number Organism UniProt Comment Textmining
1.13.11.3 Pseudomonas aeruginosa
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.13.11.3 3,4-dihydroxybenzoate + O2
-
 Pseudomonas aeruginosa 3-carboxy-cis,cis-muconate
-
 ?
1.13.11.3 3,4-dihydroxyphenylpropionic acid + O2
-
 Pseudomonas aeruginosa ?
-
 ?

Ki Value [mM]

EC Number Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
1.13.11.3 0.0005
-
 3-Fluoro-4-hydroxybenzoate
-
 Pseudomonas aeruginosa
1.13.11.3 0.0032
-
 3-Chloro-4-hydroxybenzoate
-
 Pseudomonas aeruginosa
1.13.11.3 0.018
-
 3-Bromo-4-hydroxybenzoate
-
 Pseudomonas aeruginosa
1.13.11.3 0.044
-
 3,5-Dichloro-4-hydroxybenzoate
-
 Pseudomonas aeruginosa
1.13.11.3 0.1
-
 4-hydroxybenzoate
-
 Pseudomonas aeruginosa
1.13.11.3 0.3
-
 4-Fluoro-3-hydroxybenzoate
-
 Pseudomonas aeruginosa