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Literature summary extracted from

  • Radmark, O.
    Arachidonate 5-lipoxygenase (2002), Prostaglandins, 68-69, 211-234.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
1.13.11.34 ATP stimulates Mus musculus
1.13.11.34 ATP stimulates Homo sapiens
1.13.11.34 ATP stimulates Rattus norvegicus
1.13.11.34 ATP stimulates Sus scrofa

Crystallization (Commentary)

EC Number Crystallization (Comment) Organism
1.13.11.34
-
 Oryctolagus cuniculus

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
1.13.11.34 Ca2+ stimulates Mus musculus
1.13.11.34 Ca2+ stimulates Homo sapiens
1.13.11.34 Ca2+ stimulates Rattus norvegicus
1.13.11.34 Ca2+ stimulates Sus scrofa

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
1.13.11.34 72000
-
 x * 72000, SDS-PAGE Sus scrofa
1.13.11.34 73000
-
 x * 73000, SDS-PAGE Rattus norvegicus
1.13.11.34 80000
-
 x * 80000, SDS-PAGE Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
1.13.11.34 Homo sapiens
-
-
-
1.13.11.34 Mus musculus
-
-
-
1.13.11.34 Oryctolagus cuniculus
-
-
-
1.13.11.34 Rattus norvegicus
-
-
-
1.13.11.34 Solanum tuberosum
-
-
-
1.13.11.34 Sus scrofa
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
1.13.11.34
-
 Mus musculus
1.13.11.34
-
 Homo sapiens
1.13.11.34
-
 Rattus norvegicus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.13.11.34 leukocyte
-
 Homo sapiens
-
1.13.11.34 leukocyte
-
 Rattus norvegicus
-
1.13.11.34 leukocyte
-
 Sus scrofa
-
1.13.11.34 leukocyte
-
 Oryctolagus cuniculus
-
1.13.11.34 reticulocyte
-
 Oryctolagus cuniculus
-
1.13.11.34 tuber
-
 Solanum tuberosum
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.13.11.34 arachidonate + O2 i.e. 5,8,11,14-eicosatetraenoic acid Mus musculus (6E,8Z,11Z,14Z)-(5S)-hydroperoxyicosa-6,8,11,14-tetraenoate
-
 ?
1.13.11.34 arachidonate + O2 i.e. 5,8,11,14-eicosatetraenoic acid Homo sapiens (6E,8Z,11Z,14Z)-(5S)-hydroperoxyicosa-6,8,11,14-tetraenoate
-
 ?
1.13.11.34 arachidonate + O2 i.e. 5,8,11,14-eicosatetraenoic acid Rattus norvegicus (6E,8Z,11Z,14Z)-(5S)-hydroperoxyicosa-6,8,11,14-tetraenoate
-
 ?
1.13.11.34 arachidonate + O2 i.e. 5,8,11,14-eicosatetraenoic acid Sus scrofa (6E,8Z,11Z,14Z)-(5S)-hydroperoxyicosa-6,8,11,14-tetraenoate
-
 ?
1.13.11.34 arachidonate + O2 i.e. 5,8,11,14-eicosatetraenoic acid Oryctolagus cuniculus (6E,8Z,11Z,14Z)-(5S)-hydroperoxyicosa-6,8,11,14-tetraenoate
-
 ?
1.13.11.34 arachidonate + O2 i.e. 5,8,11,14-eicosatetraenoic acid Solanum tuberosum (6E,8Z,11Z,14Z)-(5S)-hydroperoxyicosa-6,8,11,14-tetraenoate
-
 ?

Subunits

EC Number Subunits Comment Organism
1.13.11.34 ?
-
 Mus musculus
1.13.11.34 ?
-
 Solanum tuberosum
1.13.11.34 ? x * 80000, SDS-PAGE Homo sapiens
1.13.11.34 ? x * 72000, SDS-PAGE Sus scrofa
1.13.11.34 ? x * 73000, SDS-PAGE Rattus norvegicus