Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Masters, D.J.; Jacobs, V.N.; Carr, V.J.; McMillan, R.M.
    Kinetics of 5-lipoxygenase: influence of substrate solubility and product inactivation (1988), Biochem. Soc. Trans., 16, 38-39.
No PubMed abstract available

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.13.11.34 11,14,17-Eicosatrienoic acid substrate inhibition Rattus norvegicus
1.13.11.34 8,11,14-eicosatrienoic acid substrate inhibition Rattus norvegicus
1.13.11.34 arachidonic acid substrate inhibition Rattus norvegicus
1.13.11.34 docosahexaenoic acid substrate inhibition Rattus norvegicus
1.13.11.34 eicosapentaenoic acid substrate inhibition Rattus norvegicus

Organism

EC Number Organism UniProt Comment Textmining
1.13.11.34 Rattus norvegicus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.13.11.34 leukemia cell
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.13.11.34 11,14,17-eicosatrienoic acid + O2
-
 Rattus norvegicus ?
-
 ?
1.13.11.34 8,11,14-eicosatrienoic acid + O2
-
 Rattus norvegicus ?
-
 ?
1.13.11.34 arachidonate + O2 i.e. 5,8,11,14-eicosatetraenoic acid Rattus norvegicus (6E,8Z,11Z,14Z)-(5S)-hydroperoxyicosa-6,8,11,14-tetraenoate
-
 ?
1.13.11.34 docosahexaenoic acid + O2
-
 Rattus norvegicus ?
-
 ?

Temperature Stability [°C]

EC Number Temperature Stability Minimum [°C] Temperature Stability Maximum [°C] Comment Organism
1.13.11.34 37
-
 half-life: 30 s Rattus norvegicus