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Literature summary extracted from

  • Brash, A.R.; Baertschi, S.W.; Ingram, C.D.; Harris, T.M.
    On non-cyclooxygenase prostaglandin synthesis in the sea whip coral, Plexaura homomalla: an 8(R)-lipoxygenase pathway leads to formation of an alpha-ketol and a Racemic prostanoid (1987), J. Biol. Chem., 262, 15829-15839.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.13.11.40 2 arachidonic acid + 2 O2 Plexaura homomalla lipoxygenase pathway 8-hydroxy,9-oxo-eicosa-5Z,11Z,14Z-trienoic acid + 9-oxo-[8,12-cis]-prosta-5Z,10,14Z-trienoic acid + H2O
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Organism

EC Number Organism UniProt Comment Textmining
1.13.11.40 Plexaura homomalla
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sea whip coral
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Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.13.11.40 2 arachidonic acid + 2 O2 lipoxygenase pathway Plexaura homomalla 8-hydroxy,9-oxo-eicosa-5Z,11Z,14Z-trienoic acid + 9-oxo-[8,12-cis]-prosta-5Z,10,14Z-trienoic acid + H2O
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?
1.13.11.40 arachidonic acid + O2
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Plexaura homomalla (8R)-8-hydroperoxy-5,9,11,14-eicosatetraenoic acid
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