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Literature summary extracted from

  • Arciero, D.M.; Orville, A.M.; Lipscomb, J.D.
    Water and nitric oxide binding by protocatechuate 4,5-dioxygenase and catechol 2,3-dioxygenase. Evidence for binding of exogenous ligands to the active site Fe2+ of extradiol dioxygenases (1985), J. Biol. Chem., 260, 14035-14044.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.13.11.2 2-Fluorophenol
-
Pseudomonas putida
1.13.11.2 2-hydroxybenzyl alkohol
-
Pseudomonas putida
1.13.11.2 NO
-
Pseudomonas putida
1.13.11.8 3-Amino-4-hydroxybenzoic acid
-
Comamonas testosteroni
1.13.11.8 3-Chloro-4-hydroxybenzoic acid
-
Comamonas testosteroni
1.13.11.8 3-Fluoro-4-hydroxybenzoic acid
-
Comamonas testosteroni
1.13.11.8 3-Hydroxy-4-aminobenzoic acid
-
Comamonas testosteroni
1.13.11.8 3-hydroxybenzoate
-
Comamonas testosteroni
1.13.11.8 3-Iodo-4-hydroxybenzoic acid
-
Comamonas testosteroni
1.13.11.8 3-methoxy-4-hydroxybenzoic acid
-
Comamonas testosteroni
1.13.11.8 3-Nitro-4-hydroxybenzoic acid
-
Comamonas testosteroni
1.13.11.8 4-hydroxybenzoate
-
Comamonas testosteroni

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.13.11.2 0.015
-
catechol
-
Pseudomonas putida
1.13.11.2 0.05
-
4-methylcatechol
-
Pseudomonas putida
1.13.11.8 0.08
-
protocatechuate
-
Comamonas testosteroni

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
1.13.11.2 Fe2+ active site Fe2+ Pseudomonas putida

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.13.11.8 protocatechuate + O2 Comamonas testosteroni
-
4-carboxy-2-hydroxymuconate semialdehyde
-
?
1.13.11.8 protocatechuate + O2 Comamonas testosteroni Pt-L5 / ATCC 49249
-
4-carboxy-2-hydroxymuconate semialdehyde
-
?

Organism

EC Number Organism UniProt Comment Textmining
1.13.11.2 Pseudomonas putida
-
-
-
1.13.11.8 Comamonas testosteroni
-
-
-
1.13.11.8 Comamonas testosteroni
-
grown on 4-hydroxybenzoate containing medium
-
1.13.11.8 Comamonas testosteroni Pt-L5 / ATCC 49249
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.13.11.2 4-methylcatechol + O2
-
Pseudomonas putida 2-hydroxy-3-methyl-6-oxohexa-2,4-dienoate
-
?
1.13.11.2 catechol + O2
-
Pseudomonas putida 2-hydroxymuconate semialdehyde
-
?
1.13.11.8 3,4-dihydroxyphenyl sulfonate + O2
-
Comamonas testosteroni 2-hydroxy-6-oxo-4-sulfohexa-2,4-dienoate
-
?
1.13.11.8 3,4-dihydroxyphenyl sulfonate + O2
-
Comamonas testosteroni Pt-L5 / ATCC 49249 2-hydroxy-6-oxo-4-sulfohexa-2,4-dienoate
-
?
1.13.11.8 protocatechuate + O2
-
Comamonas testosteroni 4-carboxy-2-hydroxymuconate semialdehyde
-
?
1.13.11.8 protocatechuate + O2
-
Comamonas testosteroni Pt-L5 / ATCC 49249 4-carboxy-2-hydroxymuconate semialdehyde
-
?